ワタナベ ヨシコ   Yoshiko Watanabe
  渡部 芳子
   所属   川崎医科大学  医学部 臨床医学 総合臨床医学
   職種   講師
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Sex Differences in Cardiovascular Disease-Related Hospitalization and Mortality in Japan - Analysis of Health Records From a Nationwide Claim-Based Database, the Japanese Registry of All Cardiac and Vascular Disease (JROAD).
掲載誌名 正式名:Circulation journal
略  称:Circ J
ISSNコード:13474820/13469843
掲載区分国外
著者・共著者 Satsuki Noma, Katsuhito Kato, Toshiaki Otsuka, Yoko M Nakao, Rie Aoyama, Atsuko Nakayama, Atsushi Mizuno, Sachiko Kanki, Yuko Wada, Yoshiko Watanabe, Chizuko Aoki-Kamiya, Katsuyuki Hoshina, Saeko Takahashi, Yasuko Bando, Tomomi Ide, Junko Honye, Mariko Harada-Shiba, Aya Saito, Yukiko Nakano, Yasushi Sakata, Kyoko Soejima, Koji Maemura, Yayoi Tetsuou Tsukada,
発行年月 2024/06
概要 BACKGROUND:The prevalence of cardiovascular disease (CVD) is rising in Japan with its aging population, but there is a lack of epidemiological data on sex differences in CVD, including acute coronary syndrome (ACS), acute heart failure (AHF), and acute aortic disease.Methods and Results: This retrospective study analyzed data from 1,349,017 patients (January 2012-December 2020) using the Japanese Registry Of All Cardiac and Vascular Diseases database. ACS patients were youngest on average (70.5±12.9 years) and had the lowest female proportion (28.9%). AHF patients had the oldest mean age (79.7±12.0 years) and the highest proportion of females (48.0%). Acute aortic disease had the highest in-hospital mortality (26.1%), followed by AHF (11.5%) and ACS (8.9%). Sex-based mortality differences were notable in acute aortic disease, with higher male mortality in Stanford Type A acute aortic dissection (AAD) with surgery (males: 14.2% vs. females: 10.4%, P<0.001) and similar rates in Type B AAD (males: 6.2% vs. females: 7.9%, P=0.52). Aging was a universal risk factor for in-hospital mortality. Female sex was a risk factor for ACS and acute aortic disease but not for AHF or Types A and B AAD.CONCLUSIONS:Sex-based disparities in the CVD-related hospitalization and mortality within the Japanese national population have been highlighted for the first time, indicating the importance of sex-specific strategies in the management and understanding of these conditions.
DOI 10.1253/circj.CJ-23-0960
PMID 38839304