|
Syunsuke Araki
Department Kawasaki University of Medical Welfare , Position Instructor |
|
| Article types | 原著 |
| Language | English |
| Peer review | Peer reviewed |
| Title | Photopic negative response recorded with RETeval system in eyes with optic nerve disorders. |
| Journal | Formal name：Scientific reports Abbreviation：Sci Rep ISSN code：20452322/20452322 |
| Domestic / Foregin | Foregin |
| Volume, Issue, Page | 12(1),pp.9091 |
| Author and coauthor | Tsutomu Yamashita, Kumiko Kato, Mineo Kondo, Atsushi Miki, Syunsuke Araki, Katsutoshi Goto, Yoshiaki Ieki, Junichi Kiryu |
| Publication date | 2022/05 |
| Summary | Electroretinography (ERG) is used to evaluate the physiological status of the retina and optic nerve. The purpose of this study was to determine the usefulness of ERGs recorded with the RETeval system in diagnosing optic nerve diseases. Forty-eight patients with optic nerve disorders, including optic neuritis, ischemic optic neuropathy, traumatic optic neuropathy, and dominant optic atrophy, and 36 normal control subjects were studied. The amplitudes of the photopic negative response (PhNR) were recorded with the RETeval system without mydriasis. The circumpapillary retinal nerve fiber layer thickness (cpRNFLT) was determined by optical coherence tomography (OCT). The significance of the correlations between the PhNR and cpRNFLT parameters were determined, and the receiver operating curve (ROC) analyses were performed for the PhNR and cpRNFLT. Patients with optic nerve disorders had significantly smaller PhNRs compared to the control subjects (P = 0.001). The ROC analyses indicated that both PhNR and cpRNFLT had comparable diagnostic abilities of detecting optic nerve disorders with PhNR at 0.857 and cpRNFLT at 0.764. The PhNR components recorded with the RETeval system have comparable diagnostic abilities as the cpRNFLT in diagnosing optic nerve disorders. |
| DOI | 10.1038/s41598-022-12971-2 |
| PMID | 35641565 |