Norikazu Matsutomo
   Department   Kawasaki University of Medical Welfare  ,
   Position   Associate Professor with Special Assignment
Article types 原著
Language English
Peer review Peer reviewed
Title Impact of bone-equivalent solution density in a thoracic spine phantom on bone single-photon emission computed tomography image quality and quantification.
Journal Formal name：Radiological physics and technology
Abbreviation：Radiol Phys Technol
ISSN code：18650341/18650333
Domestic / ForeginDomestic
Volume, Issue, Page 16(2),pp.195-202
Author and coauthor Norikazu Matsutomo, Mitsuha Fukami, Tomoaki Yamamoto
Publication date 2023/06
Summary This study aimed to evaluate the effects of dipotassium hydrogen phosphate (K2HPO4) solution density on single-photon emission computed tomography (SPECT) image quality and quantification. We used a JSP phantom containing six cylinders filled with K2HPO4 solutions of varying densities. Computed tomography (CT) was performed, and CT values and linear attenuation coefficients were measured. Subsequently, SPECT images of an SIM2 bone phantom filled with 99mTc with/without K2HPO4 solution were acquired using a SPECT/CT camera. The full width at half maximum (FWHM), percentage coefficient of variation (%CV), recovery coefficient, and standardized uptake value (SUV) were evaluated to investigate the impact of the K2HPO4 solution density. The CT values and linear attenuation coefficients increased with the K2HPO4 solution density. The CT values for cancellous and cortical bones were reflected by K2HPO4 solution densities of 0.15-0.20 and 1.50-1.70 g/cm3, respectively. FWHM values were significantly lower with the K2HPO4 solution than those with water alone (18.0 ± 0.9 mm with water alone, 15.6 ± 0.2 mm with 0.15 g/cm3 K2HPO4, and 16.1 ± 0.3 mm with 1.49 g/cm3 K2HPO4). Although the %CVs showed no significant differences, the recovery coefficients obtained with water alone tended to be slightly lower than those obtained with the K2HPO4 solution. The SUV obtained using the standard density of the K2HPO4 solution differed from that obtained using the optimized density. In conclusion, SPECT image quality and quantification depends on the presence and concentration of the bone-equivalent solution. The optimal bone-equivalent solution density should be used to evaluate the bone image phantoms.
DOI 10.1007/s12194-023-00706-5
PMID 36877399