Shunji Endo
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of Digestive Surgery,
   Position   Associate Professor
Article types その他
Language English
Peer review Non peer reviewed
Title The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old.
Journal Formal name:Surgery today
Abbreviation:Surg Today
ISSN code:14362813/09411291
Volume, Issue, Page 53(5),pp.569-577
Author and coauthor Shunji Endo, Tomoki Yamatsuji, Yoshinori Fujiwara, Masaharu Higashida, Hisako Kubota, Hironori Tanaka, Yoshitomo Ito, Toshimasa Okada, Kazuhiko Yoshiatsu, Tomio Ueno
Publication date 2023/05
Summary PURPOSE:In Japan, the number of distal gastrectomy for patients ≥ 80 years old is increasing, whereas that of total gastrectomy is decreasing. Surgeons seem to avoid total gastrectomy for elderly patients. Total gastrectomy is reported to have a poorer prognosis than distal gastrectomy, and postoperative pneumonia may be involved in the cause.METHODS:The medical records of 39 and 108 patients ≥ 80 years old who underwent total and distal gastrectomy, respectively, at 2 affiliated institutions between 2010 and 2019 were retrospectively reviewed. Prognoses were compared between the two groups, focusing on death from pneumonia.RESULTS:The median overall survival time after total and distal gastrectomy was 21.3 and 74.1 months, respectively, with a significantly poorer prognosis after total gastrectomy than after distal gastrectomy (p < 0.01, hazard ratio [HR] 2.20, 95% confidence interval [CI] 1.37-3.53). The gastric cancer-specific survival time was significantly worse after total gastrectomy than after distal gastrectomy (p < 0.01, HR 2.73, 95% CI 1.29-5.79). The pneumonia-specific survival time was also significantly worse after total gastrectomy than after distal gastrectomy (p = 0.01, HR 3.44, 95% CI 1.25-9.48).CONCLUSIONS:Patients who underwent total gastrectomy had a poorer prognosis than those who underwent distal gastrectomy, because many patients died of pneumonia early after total gastrectomy.
DOI 10.1007/s00595-022-02599-0
PMID 36418575