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Shunji Endo
Department Kawasaki Medical School Kawasaki Medical School, Department of Digestive Surgery, Position Associate Professor |
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| Article types | 原著 |
| Language | English |
| Peer review | Peer reviewed |
| Title | Prognostic factors for cytology-positive gastric cancer. |
| Journal | Formal name：Surgery today Abbreviation：Surg Today ISSN code：14362813/09411291 |
| Domestic / Foregin | Domestic |
| Volume, Issue, Page | 49(1),pp.56-64 |
| Author and coauthor | Endo Shunji, Ikenaga Masakazu, Ohta Katsuya, Ueda Masami, Tsuda Yujiro, Kato Ryo, Itakura Hiroaki, Matsuyama Jin, Nishikawa Kazuhiro, Yamada Terumasa |
| Authorship | Lead author |
| Publication date | 2019/01 |
| Summary | PURPOSE:Positive peritoneal lavage cytology for gastric carcinoma cells (CY1) is considered distant metastasis and is classified as Stage IV. However, patients with CY1 comprise a heterogeneous population, and their prognosis varies greatly. The prognostic factors for gastric cancer patients with CY1 were retrospectively reviewed.METHODS:The participants were 80 gastric cancer patients with CY1 in our institution encountered between 2005 and 2017. Prognostic factors were analyzed using univariate and multivariate analyses.RESULTS:The operative procedure was distal gastrectomy for 30 patients, total gastrectomy for 27 patients, staging laparoscopy for 10 patients, gastrojejunostomy for 8 patients, and probe laparotomy for 5 patients. Other distant metastases were recognized in 36 patients. A multivariate analysis revealed that other distant metastases were the strongest independent risk factor for the overall survival (p < 0.0001). When the cohort was limited to CY1 patients without other distant metastases, cN2-3 (p = 0.01), the prognostic nutritional index (PNI) < 40 (p = 0.02) and Type 4 (p = 0.03) were independent risk factors according to a multivariate analysis. The survivals of patients with cN2-3 or PNI < 40 after gastrectomy were equivalent to those with other distant metastases, as assessed by log-rank analyses.CONCLUSIONS:The prognoses of CY1 gastric cancer patients with cN2-3 or PNI < 40 were poor, even after gastrectomy. |
| DOI | 10.1007/s00595-018-1704-1 |
| PMID | 30167924 |