エンドウ シュンジ   Shunji Endo
  遠藤 俊治
   所属   川崎医科大学  医学部 臨床医学 消化器外科学
   職種   准教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Treatment for gastric carcinoma in the oldest old patients.
掲載誌名 正式名:Gastric cancer
略  称:Gastric Cancer
ISSNコード:14363305/14363291
掲載区分国内
巻・号・頁 14(2),pp.139-43
著者・共著者 Endo Shunji, Yoshikawa Yukinobu, Hatanaka Nobutaka, Tominaga Harumi, Shimizu Yosuke, Hiraoka Kazuya, Nishitani Akiko, Irei Toshimitsu, Nakashima Shinsuke, Park Mi-Hwa, Takahashi Hiroyo, Wakahara Makoto, Kamiike Wataru
担当区分 筆頭著者
発行年月 2011/06
概要 BACKGROUND:The strategy for treating extremely aged patients with gastric carcinoma is controversial. This study reviews the prognoses of patients aged 85 years and older who were diagnosed with gastric carcinoma.METHODS:One hundred seventeen patients aged 85 years and older were diagnosed as having gastric carcinoma after 1969 in our institution. After excluding those at stage IV, 36 cases underwent curative resection and 30 cases received best supportive care (BSC), which we reviewed retrospectively.RESULTS:Surgical methods included distal gastrectomy for 28 cases, total gastrectomy for five cases, and other procedures for three cases. Postoperatively, pneumonia developed in four cases, anastomotic leakage in two cases, and pancreatic fistula in one case. Two patients died of pneumonia within 1 month of surgery. Univariate analysis demonstrated that age, surgery, performance status, and sodium level were statistically significant prognostic factors. Multivariate analysis demonstrated that surgery was the only independent prognostic factor. When patients with a performance status of 4 were excluded, the clinical characteristics of the surgery group (n = 36) and BSC group (n = 20) were statistically identical, and the overall survival was significantly better in the surgery group (p = 0.0078).CONCLUSIONS:Postoperative outcomes were relatively acceptable. Surgery may be feasible and beneficial even for extremely aged patients 85 years and older, except for those with a performance status of 4.
DOI 10.1007/s10120-011-0022-8
PMID 21336856