エンドウ　シュンジ   Shunji Endo   遠藤　俊治    所属   川崎医科大学  医学部 臨床医学　消化器外科学    職種   准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Effect of rikkunshito, a chinese herbal medicine, on stasis in patients after pylorus-preserving gastrectomy.
掲載誌名	正式名：World journal of surgery 略　 称：World J Surg ISSNコード：03642313/03642313
掲載区分	国外
巻・号・頁	33(2),pp.296-302
著者・共著者	Takahashi Tsuyoshi, Endo Shunji, Nakajima Kiyokazu, Souma Yoshihito, Nishida Toshirou
担当区分	2nd著者
発行年月	2009/02
概要	BACKGROUND:Distal gastrectomy (DG) and pylorus-preserving gastrectomy (PPG) have been employed for gastric cancer, with PPG having been reported to be superior to DG in regard to postoperative quality of life. Some patients with these operations still suffer from gastric stasis, however. In this study, we aimed to examine the clinical effects of rikkunshito on patients who were to undergo PPG.METHODS:A total of 11 patients who were scheduled to undergo PPG for early gastric cancer at the Osaka University Hospital were enrolled. The patients were randomly assigned to the crossover study with and without rikkunshito 7.5 g/day. Questionnaires and emptying tests using (111)In-labeled liquid scintigraphy and (99m)Tc-labeled solid scintigraphy were performed at the end of each treatment period.RESULTS:Stasis-related symptoms were significantly reduced during rikkunshito treatment (p = 0.043). The emptying test showed that rikkunshito improved emptying of solid meals (p = 0.0003) from the remnant stomach but did not accelerate gastric empting of liquid meals.CONCLUSIONS:Rikkunshito improved gastric emptying and ameliorated postoperative symptoms of patients who had undergone a PPG.
DOI	10.1007/s00268-008-9854-8
PMID	19082653