Dai Une
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of Cardiovascular Surgery,
   Position   Professor
Article types 原著
Language English
Peer review Peer reviewed
Title Lumped parameter model for hemodynamic simulation of congenital heart diseases.
Journal Formal name:The journal of physiological sciences : JPS
Abbreviation:J Physiol Sci
ISSN code:18806562/18806546
Domestic / ForeginDomestic
Volume, Issue, Page 68(2),pp.103-111
Author and coauthor Shuji Shimizu, Dai Une, Toru Kawada, Yohsuke Hayama, Atsunori Kamiya, Toshiaki Shishido, Masaru Sugimachi
Publication date 2018/03
Summary The recent development of computer technology has made it possible to simulate the hemodynamics of congenital heart diseases on a desktop computer. However, multi-scale modeling of the cardiovascular system based on computed tomographic and magnetic resonance images still requires long simulation times. The lumped parameter model is potentially beneficial for real-time bedside simulation of congenital heart diseases. In this review, we introduce the basics of the lumped parameter model (time-varying elastance chamber model combined with modified Windkessel vasculature model) and illustrate its usage in hemodynamic simulation of congenital heart diseases using examples such as hypoplastic left heart syndrome and Fontan circulation. We also discuss the advantages of the lumped parameter model and the problems for clinical use.
DOI 10.1007/s12576-017-0585-1
PMID 29270856