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イハラ トシコ
Toshiko Ito-Ihara
猪原 登志子 所属 川崎医科大学 医学部 応用医学 先端医療開発学 職種 教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Modification of 2022 ACR/EULAR ANCA-associated vasculitis classification criteria in a Japanese cohort (J-CANVAS). |
| 掲載誌名 | 正式名：Clinical and experimental rheumatology 略 称：Clin Exp Rheumatol ISSNコード：0392856X/0392856X |
| 掲載区分 | 国外 |
| 巻・号・頁 | XX(XX),pp.XX-XX |
| 著者・共著者 | Nakako Tanaka-Mabuchi, Takashi Kida, Shunichiro Hanai, Yoshiaki Kobayashi, Satoshi Omura, Yoshiyuki Abe, Masatoshi Kadoya, Naoho Takizawa, Atsushi Nomura, Yuji Kukida, Naoya Kondo, Yasuhiko Yamano, Takuya Yanagida, Koji Endo, Shintaro Hirata, Kiyoshi Matsui, Tohru Takeuchi, Kunihiro Ichinose, Masaru Kato, Ryo Yanai, Yusuke Matsuo, Yasuhiro Shimojima, Ryo Nishioka, Ryota Okazaki, Tomoaki Takata, Takafumi Ito, Mayuko Moriyama, Ayuko Takatani, Yoshia Miyawaki, Nobuyuki Yajima, Toshiko Ito-Ihara, Takashi Kawaguchi, Yutaka Kawahito, Daiki Nakagomi |
| 発行年月 | 2025/11 |
| 概要 | OBJECTIVES:The 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) classification criteria (the 2022 ACR/EULAR criteria) for anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) were recently published. This study aimed to evaluate the accuracy of these criteria in Japanese patients with AAV using data from the Japan Collaborative Registry of ANCA-associated Vasculitis (J-CANVAS).METHODS:This multicentre retrospective cohort study analysed patients with microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA), and eosinophilic granulomatosis with polyangiitis (EGPA). The 2022 ACR/EULAR criteria were applied to J-CANVAS participants to determine diagnostic performance, including sensitivity and specificity. A modified version of the 2022 ACR/EULAR criteria (the modified criteria) was subsequently developed, and its performance was compared with that of the 2022 ACR/EULAR criteria.RESULTS:In the J-CANVAS cohort, sensitivity values for MPA, GPA, and EGPA using the 2022 ACR/EULAR criteria were 96.1%, 48.5%, and 84.6%, respectively, while specificity values were 70.0%, 95.9%, and 98.0%, respectively. The modified criteria improved sensitivity to 90.7%, 83.8%, and 96.2% for MPA, GPA, and EGPA, respectively, and specificity to 86.7%, 99.0%, and 95.8%, respectively, with consistently higher AUC values.CONCLUSIONS:The modified criteria improved the accuracy of AAV classification in Japanese patients. |
| DOI | 10.55563/clinexprheumatol/5naes7 |
| PMID | 41231443 |