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ナカニシ カズオ
Kazuo Nakanishi
中西 一夫 所属 川崎医療福祉大学 リハビリテーション学部 理学療法学科 職種 教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Survival days of patients with metastatic spinal tumors of lung cancer requiring surgery: a prospective multicenter study. |
| 掲載誌名 | 正式名：Scientific reports 略 称：Sci Rep ISSNコード：20452322/20452322 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 15(1) |
| 著者・共著者 | Takuya Takahashi, Takashi Hirai, Yuki Shiratani, Akinobu Suzuki, Kenichiro Kakutani, Satoshi Kato, Hiroyuki Tominaga, Hirokazu Inoue, Hirokatsu Sawada, Norihiko Takegami, Kazuo Nakanishi, Hideaki Nakajima, Masayuki Ishihara, Tsutomu Oshigiri, Toru Funayama, Takuya Iimura, Shinji Tanishima, Hiroaki Nakashima, Daisuke Yamabe, Ko Hashimoto, Koji Uotani, Masahiro Funaba, Narihito Nagoshi, Kazu Kobayakawa, Toshitaka Yoshii, Kazuyuki Watanabe, Toshio Nakamae, Takashi Kaito, Gen Inoue, Shiro Imagama, Kota Watanabe, Takeo Furuya |
| 発行年月 | 2025/07 |
| 概要 | Surgery for metastatic spinal tumors has improved postoperative activities of daily living. A few studies reported on prognostic factors assessed in large multicenter prospective studies for metastatic spinal tumors of lung cancer origin. This study aimed to determine preoperative prognostic factors in patients undergoing surgery for metastatic spinal tumors associated with lung cancer. This prospective registry study included 74 patients diagnosed and operated with metastatic spine tumors derived from lung cancer in 39 high-volume cancer centers. We examined the postoperative survival period and the preoperative factors related to postoperative survival time. We conducted univariate and multivariate Cox regression analyses to determine preoperative prognostic factors. The mean postoperative survival period was 343 days. Multivariate Cox regression analysis revealed a higher feeding score of vitality index, indications for molecularly targeted therapy, and a higher mobility score of Barthel index as independent factors associated with postoperative survival time in metastatic spinal tumors derived from lung cancer. Patients with indications for molecular-targeted therapy and good vitality exhibited longer survival. These results may help in surgical selection for patients with metastatic spinal tumors derived from lung cancer. |
| DOI | 10.1038/s41598-025-08775-9 |
| PMID | 40619496 |