イシハマ タカノリ   Takanori Ishihama
  石濱 嵩統
   所属   川崎医科大学  医学部 臨床医学 歯科総合口腔医療学
   職種   臨床助教8年
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Correlation between prognostic nutritional index and occlusal status in gastric cancer.
掲載誌名 正式名:Oral diseases
略  称:Oral Dis
ISSNコード:16010825/1354523X
掲載区分国外
巻・号・頁 26(2),pp.465-472
著者・共著者 Atsushi Abe, Kenichi Kurita, Hiroki Hayashi, Takanori Ishihama, Akane Ueda
発行年月 2020/03
概要 OBJECTIVE:Systemic inflammatory responses in cancer patients are important factors for nutrition and prognosis. This study evaluates the association between tooth loss, occlusal status, and prognostic nutritional index (PNI).METHODS:A total of 93 patients with gastric cancer were included. These parameters were investigated the following: stage, body mass index (BMI), total lymphocyte count, C-reactive protein (CRP), PNI, and albumin (ALB). Patients were divided into three groups by Eichner classification (group A had contact in four support zones; group B had in one to three zones or in anterior region; and group C had no contact). PNI assumed 40 or less undernutrition. Multiple regression analysis was performed (PNI, dependent variable; Eichner index, main independent variable), using four independent variables (sex, age, BMI, and CRP) as adjustment factors.RESULTS:The mean ± SD PNI in groups A, B, and C was 43.0 ± 4.7, 41.7 ± 5.2, and 36.7 ± 7.7, respectively. A significant positive correlation was found between the number of teeth, both ALB, and PNI. ALB and PNI differed significantly between groups A and C (ALB, p = .0003; PNI, p = .005).CONCLUSION:We recommend a preoperative dental evaluation for assessing the nutritional status of patients with gastric cancer.
DOI 10.1111/odi.13242
PMID 31758866