モリヤ　タクヤ   Takuya Moriya   森谷　卓也    所属   川崎医科大学  医学部    職種   学長付特任教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Classification of Fibroepithelial Lesions of the Breast in Core Needle Biopsy With Implications for Further Management.
掲載誌名	正式名：Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 略　 称：Mod Pathol ISSNコード：15300285/08933952
掲載区分	国外
巻・号・頁	38(5),pp.100734
国際共著	国際共著
著者・共著者	Emad A Rakha, Cecily Quinn, Wendy Raymond, Kimberly H Allison, Sunil S Badve, Edi Brogi, Grace Callagy, Emmanuelle Charafe-Jauffret, Chih Jung Chen, Yunn-Yi Chen, Laura C Collins, Gábor Cserni, Lounes Djerroudi, Shabnam Jaffer, Maria Pia Foschini, Helenice Gobbi, Mihir Gudi, Oi Harada, Janina Kulka, Hajime Kuroda, Sunil R Lakhani, Xiaoxian Li, Takuya Moriya, Sandra A O'Toole, Sarah E Pinder, Elena Provenzano, Aysegul A Sahin, Fernando Schmitt, Abeer M Shaaban, Kalliopi P Siziopikou, Ping Tang, Gary M Tse, Zsuzsanna Varga, Anne Vincent-Salomon, Hannah Wen, Rin Yamaguchi, Wentao Yang, Stephen B Fox, Stuart J Schnitt, Ian O Ellis, Puay Hoon Tan
発行年月	2025/02
概要	Fibroepithelial lesions (FELs) of the breast represent a diverse group of biphasic tumors with varying morphologies and clinical behavior. The classification of FELs is mainly based on a constellation of diagnostic criteria, and intralesional heterogeneity is not uncommon. Therefore, reporting FELs in a core needle biopsy (CNB) with limited tissue material can be challenging as not all the features may be represented for assessment. Differentiating a classic fibroadenoma from a well-sampled phyllodes tumor (PT) is generally straightforward. However, cellular fibroadenoma, morphologically heterogeneous benign PT, and myoid hamartoma can overlap histologically. Accurate grading of PT is also challenging on CNB and carries significant management implications. In this article, we provide an overview and propose a pragmatic approach to reporting FELs on CNB, particularly for lesions with overlapping features. Guidance using the UK/European "B" classification of FELs alongside descriptive reporting of the various lesions, is also presented to aid in management decisions.
DOI	10.1016/j.modpat.2025.100734
PMID	39947480