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モリタ シュウコ
森田 周子 所属 川崎医科大学 医学部 臨床医学 消化器内科学 職種 期限付講師 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Magnifying endoscope with NBI to predict the depth of invasion in laryngo-pharyngeal cancer. |
| 掲載誌名 | 正式名：The Laryngoscope 略 称：Laryngoscope ISSNコード：15314995/0023852X |
| 掲載区分 | 国外 |
| 巻・号・頁 | 125(5),pp.1124-9 |
| 著者・共著者 | Ichiro Tateya, Shuko Morita, Manabu Muto, Shin'ichi Miyamoto, Tomomasa Hayashi, Makiko Funakoshi, Ikuo Aoyama, Shigeru Hirano, Morimasa Kitamura, Seiji Ishikawa, Yo Kishimoto, Mami Morita, Patnarin Mahattanasakul, Satoshi Morita, Juichi Ito |
| 発行年月 | 2015/05 |
| 概要 | OBJECTIVES/HYPOTHESIS:To examine if macroscopic classification with a magnifying gastrointestinal endoscope with narrow band imaging (ME-NBI) is useful in predicting pathological depth of tumor invasion in laryngo-pharyngeal cancer.STUDY DESIGN:Retrospective study.METHODS:Preoperative endoscopy reports and postoperative pathological reports on 139 laryngo-pharyngeal cancer lesions were retrospectively reviewed, and the association between macroscopic findings in the lesions and the depth of tumor invasion was analyzed statistically.RESULTS:The ratios of lesions macroscopically classified as 0-I (superficial and protruding), 0-IIa (slightly elevated), 0-IIb (true flat), 0-IIc (slightly depressed), and 0-III (superficial and excavated) in the preoperative endoscopy reports were 3%, 25%, 71%, 1%, and 0%, respectively. Regarding the depth of tumor invasion in the postoperative pathological reports, the ratios of lesions classified as EP (carcinoma in situ), SEP (tumor invades subepithelial layer), and MP (tumor invades muscularis propria) were 73%, 26%, and 1%, respectively. The ratios of subepithelial invasion or muscular invasion in 0-I, 0-IIa, and 0-IIb were 100%, 54%, and 14%, respectively, and showed significant difference (P < 0.0001). Only one of 139 lesions invaded the muscular propria.CONCLUSIONS:This study is the first one to show that macroscopic findings by ME-NBI predict the depth of tumor invasion in superficial laryngo-pharyngeal cancer. It was indicated that there is a little chance of muscular invasion if the lesion is endoscopically diagnosed as 0-I or 0-II. A new T stage classification based on the depth of tumor invasion may be needed in order to adapt the classification to include transoral surgery.LEVEL OF EVIDENCE:4. |
| DOI | 10.1002/lary.25035 |
| PMID | 25418330 |