マツトモ ノリカズ
  松友 紀和
   所属   川崎医療福祉大学  医療技術学部 診療放射線技術学科
   職種   特任准教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Combination of compressed sensing-based iterative reconstruction and offset acquisition for I-123 FP-CIT SPECT: a simulation study.
掲載誌名 正式名:Asia Oceania journal of nuclear medicine & biology
略  称:Asia Ocean J Nucl Med Biol
ISSNコード:23225718/23225718
掲載区分国外
巻・号・頁 10(2),pp.117-125
著者・共著者 Norikazu Matsutomo, Takeyuki Hashimoto, Mitsuha Fukami, Tomoaki Yamamoto
発行年月 2022
概要 OBJECTIVES:The purpose of this study was to validate undersampled single-photon emission computed tomography (SPECT) imaging using a combination of compressed sensing (CS) iterative reconstruction (CS-IR) and offset acquisition.METHODS:Three types of numerical phantoms were used to evaluate image quality and quantification derived from CS with offset acquisition. SPECT images were reconstructed using filtered back-projection (FBP), maximum likelihood-expectation maximization (ML-EM), CS-IR, and CS-IR with offset acquisition. The efficacy of CS-IR with offset acquisition was examined in terms of spatial resolution, aspect ratio (ASR), activity concentration linearity, contrast, percent coefficient of variation (%CV), and specific binding ratio (SBR).RESULTS:The full widths at half maximum remained unchanged as the number of projections decreased in CS-IR with offset acquisition. Changes in ASRs and linearities of count density were observed for ML-EM and CS-IR from undersampled projections. The %CV obtained by CS-IR with offset acquisition was substantially lower than that obtained by ML-EM and CS-IR. There were no significant differences between the %CVs obtained from 60 projections by CS-IR with offset acquisition and from 120 projections by FBP. Although the SBRs for CS-IR with offset acquisition tended to be slightly lower than for FBP, the SBRs for CS-IR with offset acquisition did not change with the number of projections.CONCLUSIONS:CS-IR with offset acquisition can provide good image quality and quantification compared with a commonly used SPECT reconstruction method, especially from undersampled projection data. Our proposed method could shorten overall SPECT acquisition times, which would benefit patients and enable quantification with dynamic SPECT acquisitions.
DOI 10.22038/AOJNMB.2021.59585.1417
PMID 35800416