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マツトモ ノリカズ
松友 紀和 所属 川崎医療福祉大学 医療技術学部 診療放射線技術学科 職種 特任准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Optimization of scatter estimation window setting for quantitative analysis in 111In-pentetreotide single photon emission computed tomography imaging. |
| 掲載誌名 | 正式名：Hellenic journal of nuclear medicine 略 称：Hell J Nucl Med ISSNコード：17905427/17905427 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 23(3),pp.223-228 |
| 著者・共著者 | Mizuho Hishikawa, Norikazu Matsutomo, Tomoaki Yamamoto |
| 発行年月 | 2020 |
| 概要 | OBJECTIVE:The aim of this study was to validate the optimal scatter correction method and scatter estimation window setting in terms of image quality and quantitative accuracy for quantitative indium-111 (111In)-pentetreotide SPECT imaging.MATERIALS AND METHODS:We used a positron emission tomography/computed tomography (PET/CT) phantom to validate image quality and quantitative accuracy, and the SPECT images were acquired by the multi-energy window (MEW) method. The scatter estimation was performed using four kinds of energy windows (MEW1, MEW2, MEW3, and MEW4). Scatter correction was also performed using a dual-energy window (DEW) for comparison with MEWs. Image quality was assessed using percent contrast (% contrast) and background variability, and quantitative accuracy was assessed using the mean standardized uptake value (SUVmean) with hot spheres.RESULTS:In the quantification, all MEW settings approached the theoretical SUVmean (MEW1, 0.99±0.06; MEW2, 0.99±0.05; MEW3, 1.00±0.08; MEW4, 0.97±0.12) in contrast to DEW (0.88±0.05). The SUVmean value for scatter correction of both photopeaks for a 28 mm sphere showed the smallest difference from the theoretical value.CONCLUSION:The scatter correction method that gave optimal image quality and quantitative accuracy was MEW3 with two 20% energy windows (one over each photopeak) and four adjacent 3% scatter estimation windows (one on each side of the two photopeaks). |
| DOI | 10.1967/s002449912200 |
| PMID | 33306751 |