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マツトモ ノリカズ
松友 紀和 所属 川崎医療福祉大学 医療技術学部 診療放射線技術学科 職種 特任准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Evaluation of a novel normal database with matched SPECT systems and optimal pre-filter parameters for 3D-SSP. |
| 掲載誌名 | 正式名：Annals of nuclear medicine 略 称：Ann Nucl Med ISSNコード：18646433/09147187 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 26(1),pp.16-25 |
| 著者・共著者 | Hideo Onishi, Norikazu Matsutomo, Yuji Kai, Yoshiharu Kangai, Hizuru Amijima, Takeshi Yamaguchi |
| 発行年月 | 2012/01 |
| 概要 | PURPOSE:A normal perfusion database (NDB) is imperative for the statistical imaging of brain function. This study validates a novel NDB created under the same injection dose and acquisition conditions for three gamma camera systems and evaluates optimal pre-filter parameters for three-dimensional stereotactic surface projections (3D-SSPs).METHOD:We compared a novel NDB that matched the databases in each of three vendor gamma camera systems with a conventionally constructed NDB (conventional NDB) and a NDB constructed in-house for 3D-SSP. We generated hypoperfused regions where pre-specified volumes were simulated for various areas in SPECT images. The properties of each NDB were evaluated based on the distribution of the standard deviation (SD). Abnormal accumulation regions were validated using Z, extent, and artifactual scores. Detection error was used to evaluate the optimal Butterworth pre-filter cutoff frequency with the perfusion defect rate (PDR) in 3D-SSP.RESULTS:The SD distribution was the same in the novel NDB and in the NDB constructed in-house, and the SD of the peak distribution was 0.08-0.07. The Z and extent scores of the novel DB and the NDB constructed in-house were similar, but increased along with the artifactual scores when using the conventional NDB. Many artifacts appeared in the Z score map when using the conventional NDB. The detection error deviated from the actual value by -1.3% at a cutoff frequency of 0.58 cycles/cm and a PDR of 30%, which was the lowest. The cutoff frequency became lower or higher, and the low-perfusion defect rate increased according to the increasing detection error. The optimal cutoff frequency was between 0.52 and 0.58 cycles/cm.CONCLUSIONS:We generated a novel NDB according to the individual devices and compared it with a conventional and a NDB constructed in-house. The Z and extent scores were essentially equal when using the novel DB and the NDB constructed in-house, but considerably differed when using the conven |
| DOI | 10.1007/s12149-011-0534-7 |
| PMID | 21909693 |