ナカニシ カズオ   Kazuo Nakanishi
  中西 一夫
   所属   川崎医療福祉大学  リハビリテーション学部 理学療法学科
   職種   教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Effects of Palliative Surgical Treatment for Spinal Metastases on the Patient's Quality of Life With a Focus on the Segment of the Metastasis: A Prospective Multicenter Study.
掲載誌名 正式名:Global spine journal
略  称:Global Spine J
ISSNコード:21925682/21925682
掲載区分国外
巻・号・頁 pp.21925682241297948
著者・共著者 Naoki Segi, Hiroaki Nakashima, Sadayuki Ito, Jun Ouchida, Yuki Shiratani, Takaki Shimizu, Akinobu Suzuki, Hidetomi Terai, Kenichiro Kakutani, Yutaro Kanda, Hiroyuki Tominaga, Ichiro Kawamura, Masayuki Ishihara, Masaaki Paku, Yohei Takahashi, Masahiro Funaba, Toru Funayama, Hideaki Nakajima, Koji Akeda, Takashi Hirai, Hirokazu Inoue, Kazuo Nakanishi, Haruki Funao, Tsutomu Oshigiri, Bungo Otsuki, Kazu Kobayakawa, Shinji Tanishima, Ko Hashimoto, Takuya Iimura, Hirokatsu Sawada, Koji Uotani, Hiroaki Manabe, Chizuo Iwai, Daisuke Yamabe, Akihiko Hiyama, Shoji Seki, Yuta Goto, Masashi Miyazaki, Kazuyuki Watanabe, Toshio Nakamae, Takashi Kaito, Narihito Nagoshi, Satoshi Kato, Kota Watanabe, Shiro Imagama, Gen Inoue, Takeo Furuya
発行年月 2024/11/01
概要 STUDY DESIGN:Prospective multicenter study.OBJECTIVES:Palliative surgery is crucial for maintaining the quality of life (QOL) in patients with spinal metastases. This study aimed to compare the short-term outcomes of QOL after palliative surgery between patients with metastatic spinal tumors at different segments.METHODS:We prospectively compared the data of 203 patients with spinal metastases at 2-3 consecutive segments who were divided into the following three groups: cervical, patients with cervical spine lesions; thoracic, patients with upper-middle thoracic spine lesions; and TL/L/S, patients with lesions at the thoracolumbar junction and lumbar and sacral regions. Preoperative and postoperative EuroQol 5-dimension (EQ5D) 5-level were compared.RESULTS:All groups exhibited improvement in the Frankel grade, performance status, pain, Barthel index, EQ5D health state utility value (HSUV), and EQ5D visual analog scale (VAS) postoperatively. Although preoperative EQ5D HSUVs did not significantly differ between the groups (cervical, 0.461 ± 0.291; thoracic, 0.321 ± 0.292; and TL/L/S, 0.376 ± 0.272), the thoracic group exhibited significantly lower postoperative EQ5D HSUVs than the other two groups (cervical, 0.653 ± 0.233; thoracic, 0.513 ± 0.252; and TL/L/S, 0.624 ± 0.232). However, postoperative EQ5D VAS was not significantly different between the groups (cervical, 63.4 ± 25.8; thoracic, 54.7 ± 24.5; and TL/L/S, 61.7 ± 21.9).CONCLUSIONS:Palliative surgery for metastatic spinal tumors provided comparable QOL improvement, irrespective of the spinal segment involved. Patients with upper and middle thoracic spinal metastases had poorer QOL outcomes than those with metastases in other segments; however, sufficient QOL improvement was achieved.
DOI 10.1177/21925682241297948
PMID 39484810