スギヤマ　ヒトシ   杉山　斉    所属   川崎医療短期大学  教育部 医療介護福祉学科    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Renal pathology in adult and paediatric population of Japan: review of the Japan renal biopsy registry database from 2007 to 2017.
掲載誌名	正式名：J Nephrol.
掲載区分	国外
巻・号・頁	36(8),pp.2257-2267
著者・共著者	Kazunori Goto, Takahiro Imaizumi, Riku Hamada, Kenji Ishikura, Tomoki Kosugi, Ichiei Narita, Hitoshi Sugiyama, Akira Shimizu, Hitoshi Yokoyama, Hiroshi Sato, Shoichi Mauryama
発行年月	2023/11
概要	Background This study aimed to summarise the epidemiology of biopsy-diagnosed kidney disease in Japan over 10 years. Methods We analysed the J-RBR database, from 2007 to 2017. Patients’ clinical data collected at the time of biopsy and histopathological diagnoses were used for epidemiological and clinicopathologic analyses. Results The predominant renal biopsy diagnoses were immunoglobulin A nephropathy (39.2%), lupus nephritis (6.5%) and minimal change disease (6.0%) in younger adults (19–64 years), and membranous nephropathy (17.4%), antineutrophil cytoplasmic antibody-associated vasculitis or anti-glomerular basement membrane glomerulonephritis (13.0%), and immunoglobulin A nephropathy (12.5%) in older adults (≥ 65 years). The percentages of patients diagnosed with membranoproliferative glomerulonephritis and immunoglobulin A nephropathy decreased, whereas those with immunoglobulin A vasculitis and diabetic nephropathy increased over the decade. In paediatric patients (< 19 years), immunoglobulin A nephropathy (36.1%), minimal change disease (17.6%), and immunoglobulin A vasculitis (8.6%) were the predominant diagnoses. The percentage of patients diagnosed with immunoglobulin A vasculitis increased over the decade. Based on the sex distribution, minimal change disease and membranous nephropathy were predominant in men aged < 20 and > 40 years, respectively, whereas immunoglobulin A vasculitis and antineutrophil cytoplasmic antibody-associated vasculitis or anti-glomerular basement membrane glomerulonephritis were predominant in women in their 20s and 30s and aged < 50 years, respectively. Immunoglobulin A nephropathy was predominant in men at most ages and in women in their 20s to 40s. Conclusions This study describes the distribution and changes in kidney biopsy diagnoses over 10 years in Japan and paves the way for future research on kidney diseases in adults and children.
DOI	10.1007/s40620-023-01687-9.
PMID	37597092