スギモト　コウヘイ   杉本　昂平    所属   川崎医療福祉大学  医療技術学部 診療放射線技術学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Usefulness of Simple Diffusion Kurtosis Imaging for Head and Neck Tumors: An Early Clinical Study.
掲載誌名	正式名：Acta medica Okayama 略　 称：Acta Med Okayama ISSNコード：0386300X/0386300X
掲載区分	国内
巻・号・頁	77(3),pp.273-280
著者・共著者	Yudai Shimizu, Masahiro Kuroda, Yuki Nakamitsu, Wlla E Al-Hammad, Suzuka Yoshida, Yuka Fukumura, Yoshihide Nakamura, Kazuhiro Kuroda, Ryo Kamizaki, Satoshi Imajoh, Yoshinori Tanabe, Kohei Sugimoto, Masataka Oita, Irfan Sugianto, Babatunde O Bamgbose, Yoshinobu Yanagi, Junichi Asaumi
発行年月	2023/06
概要	Diffusion kurtosis (DK) imaging (DKI), a type of restricted diffusion-weighted imaging, has been reported to be useful for tumor diagnoses in clinical studies. We developed a software program to simultaneously create DK images with apparent diffusion coefficient (ADC) maps and conducted an initial clinical study. Multi-shot echo-planar diffusion-weighted images were obtained at b-values of 0, 400, and 800 sec/mm2 for simple DKI, and DK images were created simultaneously with the ADC map. The usefulness of the DK image and ADC map was evaluated using a pixel analysis of all pixels and a median analysis of the pixels of each case. Tumor and normal tissues differed significantly in both pixel and median analyses. In the pixel analysis, the area under the curve was 0.64 for the mean kurtosis (MK) value and 0.77 for the ADC value. In the median analysis, the MK value was 0.74, and the ADC value was 0.75. The MK and ADC values correlated moderately in the pixel analysis and strongly in the median analysis. Our simple DKI system created DK images simultaneously with ADC maps, and the obtained MK and ADC values were useful for differentiating head and neck tumors from normal tissue.
DOI	10.18926/AMO/65492
PMID	37357628