スズキ ケイタ   Keita Suzuki
  鈴木 啓太
   所属   川崎医療福祉大学  リハビリテーション学部 理学療法学科
   職種   助教
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 Relationship between handgrip strength and albuminuria in community-dwelling elderly Japanese subjects: the Shika Study.
掲載誌名 正式名:Biomarkers
略  称:Biomarkers
ISSNコード:13665804/1354750X
掲載区分国外
巻・号・頁 25(7),pp.587-593
著者・共著者 Akinori Hara, Hiromasa Tsujiguchi, Keita Suzuki, Yuichi Tao, Haruki Nakamura, Tomoko Kasahara, Thao Thi Thu Nguyen, Sakae Miyagi, Yukari Shimizu, Takayuki Kannon, Atsushi Tajima, Takashi Wada, Toshinari Takamura, Hiroyuki Nakamura
発行年月 2020/11
概要 PURPOSE:This study aimed to investigate the association between handgrip strength (HGS) and albuminuria in the general population of Japan as per sex and age.METHODS:This population-based, cross-sectional study enrolled 916 Japanese participants aged ≥40 years. Albuminuria was measured and expressed as the urinary albumin-to-creatinine ratio (UACR). Biochemical, nutritional, and anthropometric profiles as well as HGS were measured using standardised protocols.RESULTS:Four hundred and thirty-two (47%) of the study participants were men, and 484 were women, with respective mean ages of 62 ± 11 years and 63 ± 11 years. HGS, older age, high body mass index, presence of hypertension or diabetes, and a decreased estimated glomerular filtration rate were correlated with the log-transformed UACR in subjects of both sexes. Multivariate linear regression analysis showed that HGS was independently associated with the log UACR in both, men [beta coefficient -0.43; 95% confidence interval (CI) -0.73, -0.13] and women (beta coefficient -0.50; 95% CI -0.90, -0.10) aged ≥65 years; however, a similar association was not observed in younger participants.CONCLUSION:Low HGS was associated with albuminuria in older men and women in Japan.
DOI 10.1080/1354750X.2020.1819418
PMID 32893687