スズキ　ケイタ   Keita Suzuki   鈴木　啓太    所属   川崎医療福祉大学  リハビリテーション学部 理学療法学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Gender difference in the association of dietary intake of antioxidant vitamins with kidney function in middle-aged and elderly Japanese.
掲載誌名	正式名：Journal of nutritional science 略　 称：J Nutr Sci ISSNコード：20486790/20486790
掲載区分	国外
巻・号・頁	10,pp.e2
著者・共著者	Akinori Hara, Hiromasa Tsujiguchi, Keita Suzuki, Fumihiko Suzuki, Tomoko Kasahara, Pham Kim Oanh, Sakae Miyagi, Takayuki Kannon, Atsushi Tajima, Takashi Wada, Hiroyuki Nakamura
発行年月	2021
概要	Dietary intake modification is important for the treatment of chronic kidney disease (CKD); however, little is known about the association between dietary intake of antioxidant vitamins and kidney function based on gender difference. We examined the relationship of dietary intake of antioxidant vitamins with decreased kidney function according to gender in Japanese subjects. This population-based, cross-sectional study included 936 Japanese participants with the age of 40 years or older. A validated brief self-administered diet history questionnaire was used to measure dietary intakes of vitamin E and its four isoforms, vitamin A and vitamin C. Decreased kidney function was defined as estimated glomerular filtration rate <60 ml/min/1·73 m2. A total of 498 (53·2 %) of the study participants were women. Mean age was 62·4 ± 11·3 years. Overall, 157 subjects met the criteria of decreased kidney function. In the fully adjusted model, a high vitamin E intake is inversely associated with decreased kidney function in women (odds ratio, 0·886; 95 % confidence interval, 0·786-0·998), whereas vitamin E intake was not associated with decreased kidney function (odds ratio, 0·931; 95 % confidence interval, 0·811-1·069) in men. No significant association between dietary intake of vitamins A and C and decreased kidney function was observed in women and men. Higher dietary intake of vitamin E was inversely associated with decreased kidney function in middle-aged and older women, and the result may provide insight into the more tailored dietary approaches to prevent CKD.
DOI	10.1017/jns.2020.54
PMID	33889385