スズキ　ケイタ   Keita Suzuki   鈴木　啓太    所属   川崎医療福祉大学  リハビリテーション学部 理学療法学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Association between Dietary Fat Intake and Hyperuricemia in Men with Chronic Kidney Disease.
掲載誌名	正式名：Nutrients 略　 称：Nutrients ISSNコード：20726643/20726643
掲載区分	国外
巻・号・頁	14(13)
著者・共著者	Fumika Oku, Akinori Hara, Hiromasa Tsujiguchi, Keita Suzuki, Kim-Oanh Pham, Fumihiko Suzuki, Sakae Miyagi, Masaharu Nakamura, Chie Takazawa, Kuniko Sato, Toru Yanagisawa, Takayuki Kannon, Atsushi Tajima, Hiroyuki Nakamura
発行年月	2022/06
概要	Despite a close relationship between chronic kidney disease (CKD) and uric acid level, few studies have examined the relationship between uric acid level and fat intake by kidney function status. Therefore, we investigated the association between dietary fat intake and hyperuricemia with and without decreased kidney function in males living in Shika Town, Ishikawa Prefecture, Japan. This study included 361 males with a mean age of 60.7 years. Dietary fat and fatty acid intakes were evaluated using the brief-type self-administered diet history questionnaire. Reduced kidney function was defined as an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m2, while hyperuricemia was defined as a serum uric acid level >7.0 mg/dL. A two-way analysis of covariance showed that saturated fatty acid (p = 0.026), monounsaturated fatty acid (p = 0.014), and polyunsaturated fatty acid (p = 0.022) were significantly lower in the high uric acid group than in the normal uric acid group. In multiple logistic analysis stratified by renal function, lipid intake was negatively associated with hyperuricemia in the low eGFR group. These findings suggest that higher dietary lipid/fatty acid intake may be effective in the prevention and treatment of hyperuricemia in men with CKD.
DOI	10.3390/nu14132637
PMID	35807818