トクトミ　トモハル   Tomoharu Tokutomi   徳富　智明    所属   川崎医科大学  医学部 臨床医学　小児科学    職種   特任教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Characteristic profile of intestinal microflora in Kawasaki disease
掲載誌名	正式名：ACTA PAEDIATRICA ISSNコード：0803-5253
出版社	TAYLOR & FRANCIS AS
巻・号・頁	91(7),pp.783-788
著者・共著者	S Takeshita,Kobayashi, I,Y Kawamura,T Tokutomi,Sekine, I
発行年月	2002
概要	To investigate whether the ecology of the intestinal microflora may change in the acute phase of Kawasaki disease (KD), the distribution pattern was studied of common micro-organisms in feces from 20 patients with KD, 20 patients with acute febrile diseases (disease control) and 20 healthy children. KD patients had a significantly lower (p < 0.001) incidence of Lactobacillus (2/20, 10%) than disease control patients (16/20, 80%) and healthy children (14/20, 70%). KD patients had no significant incidences of other microbial genera, compared with both disease control and healthy children. Conclusion: The results suggest that a lack or loss of the beneficial Lactobacillus genus in the enteric microflora may occur during the acute phase of KD.