フククラ ヨシヒコ   Yoshihiko Fukukura
  福倉 良彦
   所属   川崎医科大学  医学部 臨床医学 機能・代謝画像診断学
   職種   教授
論文種別 原著
言語種別 英語
査読の有無 査読あり
表題 [Hepatocellular carcinoma treated by intraarterial injection of adriamycin/mitomycin C oil suspension alone or combined with cis-diaminodichloroplatinum].
掲載誌名 正式名:Gan to kagaku ryoho. Cancer & chemotherapy
ISSNコード:03850684
掲載区分国内
巻・号・頁 20,pp.1049-1053
著者・共著者 Inoue H, Miyazono N, Hori A, Kanetsuki I, Tanaka D, Fukukura Y, Tsuchimochi S, Hokotate H, Ida K, Ikeda K, et al.
発行年月 1993/06
概要 One hundred thirty-five patients with hepatocellular carcinoma (HCC) were treated by intraarterial injection of adriamycin/mitomycin C oil suspension (ADMOS) alone (59 cases) and ADMOS plus cis-diaminodichloroplatinum (CDDP) (76 cases). Tumor size was reduced by over 25% in 13 of 38 patients (35%) in the ADMOS alone group and in 39 of 76 patients (50%) in the ADMOS plus CDDP group. Serum alpha-fetoprotein (AFP) levels decreased by more than 50% in 7/17 (59%) in the ADMOS alone group and in 23/32 (70%) in the ADMOS plus CDDP group. The overall 1- and 2-year survival rates were 68% and 41% by the Kaplan-Meier method. However, no significant difference in the survival rates was observed between the two groups.