フククラ　ヨシヒコ   Yoshihiko Fukukura   福倉　良彦    所属   川崎医科大学  医学部 臨床医学　機能・代謝画像診断学    職種   教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	Characterization of adrenal tumors by chemical shift fast low-angle shot MR imaging: comparison of four methods of quantitative evaluation.
掲載誌名	正式名：AJR. American journal of roentgenology 略　 称：AJR Am J Roentgenol ISSNコード：0361803X/0361803X
掲載区分	国外
巻・号・頁	180(6),pp.1649-1657
著者・共著者	Fumito Fujiyoshi, Masayuki Nakajo, Yoshihiko Fukukura, Shinsaku Tsuchimochi
発行年月	2003/06
概要	OBJECTIVE:The aim of our study was to assess quantitative methods of distinguishing adenomas from malignant adrenal lesions using chemical shift fast low-angle shot MR imaging.MATERIALS AND METHODS:We assessed 102 adrenal tumors in 88 patients (27 hyperfunctioning and 44 nonhyperfunctioning adenomas, 19 metastases, nine pheochromocytomas, and three other adrenal tumors) using chemical shift MR imaging. On the chemical shift imaging, signal intensity index, calculated as [(signal intensity on in-phase imaging - signal intensity on opposed-phase imaging) / (signal intensity on in-phase imaging)] x 100%, was compared with the adrenal-to-spleen ratio, adrenal-to-muscle ratio, and adrenal-to-liver ratio for signal change on opposed-phase fast low-angle shot MR imaging. The tissues in the spleen, paraspinal muscle, and liver were reference tissues.RESULTS:The signal intensity index had several advantages over the other three parameters calculated. We found no overlap in indexes between adenomas and metastatic tumors. The accuracy in distinguishing adenomas from metastatic tumors was 100% if the cutoff value of the signal intensity index selected was 11.2-16.5%.CONCLUSION:The signal intensity index is the most reliable evaluation method for differentiating adrenal adenomas from metastatic adrenal tumors.
DOI	10.2214/ajr.180.6.1801649
PMID	12760936