アラキ　シュンスケ   Syunsuke Araki   荒木　俊介    所属   川崎医療福祉大学  リハビリテーション学部 視能療法学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Photopic negative response recorded with RETeval system in eyes with optic nerve disorders.
掲載誌名	正式名：Scientific reports 略　 称：Sci Rep ISSNコード：20452322/20452322
掲載区分	国外
巻・号・頁	12(1),pp.9091
著者・共著者	Tsutomu Yamashita, Kumiko Kato, Mineo Kondo, Atsushi Miki, Syunsuke Araki, Katsutoshi Goto, Yoshiaki Ieki, Junichi Kiryu
発行年月	2022/05
概要	Electroretinography (ERG) is used to evaluate the physiological status of the retina and optic nerve. The purpose of this study was to determine the usefulness of ERGs recorded with the RETeval system in diagnosing optic nerve diseases. Forty-eight patients with optic nerve disorders, including optic neuritis, ischemic optic neuropathy, traumatic optic neuropathy, and dominant optic atrophy, and 36 normal control subjects were studied. The amplitudes of the photopic negative response (PhNR) were recorded with the RETeval system without mydriasis. The circumpapillary retinal nerve fiber layer thickness (cpRNFLT) was determined by optical coherence tomography (OCT). The significance of the correlations between the PhNR and cpRNFLT parameters were determined, and the receiver operating curve (ROC) analyses were performed for the PhNR and cpRNFLT. Patients with optic nerve disorders had significantly smaller PhNRs compared to the control subjects (P = 0.001). The ROC analyses indicated that both PhNR and cpRNFLT had comparable diagnostic abilities of detecting optic nerve disorders with PhNR at 0.857 and cpRNFLT at 0.764. The PhNR components recorded with the RETeval system have comparable diagnostic abilities as the cpRNFLT in diagnosing optic nerve disorders.
DOI	10.1038/s41598-022-12971-2
PMID	35641565