アラキ　シュンスケ   Syunsuke Araki   荒木　俊介    所属   川崎医療福祉大学  リハビリテーション学部 視能療法学科    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Macular retinal and choroidal thickness in unilateral amblyopia using swept-source optical coherence tomography.
掲載誌名	正式名：BMC ophthalmology 略　 称：BMC Ophthalmol ISSNコード：14712415/14712415
掲載区分	国外
巻・号・頁	17(1),pp.167
著者・共著者	Syunsuke Araki, Atsushi Miki, Katsutoshi Goto, Tsutomu Yamashita, Go Takizawa, Kazuko Haruishi, Yoshiaki Ieki, Junichi Kiryu, Kiyoshi Yaoeda
担当区分	筆頭著者
発行年月	2017/09
概要	BACKGROUND:To investigate macular retinal and choroidal thickness in amblyopic eyes compared to that in fellow and normal eyes using swept-source optical coherence tomography (SS-OCT).METHODS:This study examined 31 patients with hyperopic anisometropic amblyopia (6.9 ± 3.8 years, mean ± standard deviation), 15 patients with strabismic amblyopia without anisometropia (7.9 ± 4.2 years), and 24 age-matched controls (7.8 ± 3.3 years). Retinal and choroidal thickness was measured by 3D scans using SS-OCT. A 6-mm area around the fovea was automatically analyzed using the Early Treatment Diabetic Retinopathy Study map. The thickness from SS-OCT was corrected for magnification error using individual axial length, spherical refraction, cylinder refraction, and corneal radius. Retinal thickness was divided into the macular retinal nerve fiber layer (mRNFL), ganglion cell layer + inner plexiform layer (GCL+IPL), ganglion cell complex (GCC), and the inner limiting membrane to the retinal pigment epithelium (ILM-RPE) thickness. Retinal and choroidal thickness was compared among amblyopic, fellow, and normal eyes.RESULTS:In both amblyopia groups, there was no significant difference in the mRNFL, GCL+IPL, and GCC thicknesses among the amblyopic, fellow, and control eyes. In the anisometropic amblyopia group, choroidal thickness (subfovea, center 1 mm, nasal and inferior of the inner ring, nasal of the outer ring, and center 6 mm) of amblyopic eyes were significantly greater than that of fellow and normal eyes. In contrast, none of the choroidal thicknesses were significantly different among the investigated eyes in the strabismic amblyopia group.CONCLUSIONS:We found no significant difference in inner retinal thickness in patients with unilateral amblyopia. Although there were significant differences in choroidal thickness with hyperopic anisometropic amblyopia, there was no significant difference for the strabismic amblyopia. The discrepancy in choroidal thickness between the two
DOI	10.1186/s12886-017-0559-3
PMID	28915835