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ヤノ シュウヤ
Shuya Yano
矢野 修也 所属 川崎医科大学 医学部 臨床医学 消化器外科学 職種 講師 |
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| 論文種別 | 症例報告 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | Long-term survival without recurrence after surgery for gastric yolk sac tumor-like carcinoma: a case report. |
| 掲載誌名 | 正式名：Surgical case reports 略 称：Surg Case Rep ISSNコード：21987793/21987793 |
| 掲載区分 | 国外 |
| 巻・号・頁 | 7(1),pp.111 |
| 著者・共著者 | Umeda Hibiki, Kikuchi Satoru, Kuroda Shinji, Yano Shuya, Tanaka Takehiro, Noma Kazuhiro, Nishizaki Masahiko, Kagawa Shunsuke, Umeda Yuzo, Fujiwara Toshiyoshi |
| 発行年月 | 2021/05 |
| 概要 | BACKGROUND:Gastric yolk sac tumor (YST)-like carcinoma is extremely rare, and its prognosis is poor, because most patients have widespread metastases at the time of diagnosis. We report a case of gastric YST-like carcinoma with an adenocarcinoma component without metastases in which curative resection was performed.CASE PRESENTATION:A 77-year-old man complaining of melena and dizziness due to anemia was diagnosed with poorly differentiated adenocarcinoma in the gastric cardia, with a benign ulcer in the gastric body. He underwent total gastrectomy with D2 lymph node dissection for the tumor. Histological examination of the resected specimens revealed a mixture of reticular and glandular neoplastic components morphologically. In the reticular area, an endodermal sinus pattern and some Schiller-Duval bodies were confirmed. Gastric YST-like carcinoma with adenocarcinoma components, T2N0M0 Stage IB, was diagnosed. Immunohistochemical analysis showed that the YST was positive for carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP) and p53. In contrast, the adenocarcinoma was positive for p53 and negative for CEA and AFP. The patient remained healthy as of 7 years postoperatively, with no recurrence.CONCLUSIONS:Routine medical examinations or endoscopic examinations for accidental symptom may be helpful for early diagnosis and good prognosis for gastric YST-like carcinoma, although the prognosis is generally poor. |
| DOI | 10.1186/s40792-021-01199-3 |
| PMID | 33956241 |