トノムラ　ソウタツ   Sotatsu Tonomura   外村　宗達    所属   川崎医科大学  医学部 基礎医学　解剖学    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	How many hair follicles are innervated by one afferent axon? A confocal microscopic analysis of palisade endings in the auricular skin of thy1-YFP transgenic mouse
掲載誌名	正式名：Proc Jpn Acad Ser B Phys Biol Sci
掲載区分	国内
巻・号・頁	88(10),pp.583-95
著者・共著者	Suzuki, M. Ebara, S. Koike, T. Tonomura, S. Kumamoto, K.
発行年月	2012
概要	Hairs are known as a sensory apparatus for touch. Their follicles are innervated predominantly by palisade endings composed of longitudinal and circumferential lanceolate endings. However, little is known as to how their original primary neurons make up a part of the ending. In this study, innervation of the palisade endings was investigated in the auricular skin of thy1-YFP transgenic mouse. Major observations were 1) Only a small portion of PGP9.5-immunopositive axons showed YFP-positivity, 2) All of thy1-YFP-positive sensory axons were thick and myelinated, 3) Individual thy1-YFP-positive trunk axons innervated 4-54 hair follicles, 4) Most palisade endings had a gap of lanceolate ending arrangement, 5) PGP9.5-immunopositive 10-32 longitudinal lanceolate endings were closely arranged. Only a part of them were thy1-YFP-positive axons that originated from 1-3 afferents, and 6) Single nerve bundles of the dermal nerve network included both bidirectional afferents. Palisade endings innervated by multiple sensory neurons might be highly sensitive to hair movement.
DOI	10.2183/pjab.88.583
文献番号	23229751