トノムラ ソウタツ
Sotatsu Tonomura
外村 宗達 所属 川崎医科大学 医学部 基礎医学 解剖学 職種 助教 |
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論文種別 | 原著 |
言語種別 | 英語 |
査読の有無 | 査読あり |
表題 | Protocol for pressure-clamped patch-clamp recording at the node of Ranvier of rat myelinated nerves |
掲載誌名 | 正式名:STAR Protoc ISSNコード:26661667 |
掲載区分 | 国外 |
巻・号・頁 | 2(1),pp.100266 |
著者・共著者 | Kanda, H. Tonomura, S. Dai, Y. Gu, J. G. |
発行年月 | 2021 |
概要 | The patch-clamp recording technique is indispensable for studying ion channel functions of cells but is challenging to apply to the node of Ranvier, a key site where action potentials are conducted along myelinated nerves. We have developed a pressure-clamped patch-clamp recording method applying to the node of Ranvier of rat myelinated nerves. The step-by-step protocol described here allows researchers to apply this approach to study mechanisms underlying saltatory conduction and information processing in myelinated nerves of mammals. For complete information on the generation and use of this protocol, please refer to Kanda et al. (2019). |
DOI | 10.1016/j.xpro.2020.100266 |
文献番号 | 33490982 |