トノムラ　ソウタツ   Sotatsu Tonomura   外村　宗達    所属   川崎医科大学  医学部 基礎医学　解剖学    職種   助教
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Structure-function correlations of rat trigeminal primary neurons: Emphasis on club-like endings, a vibrissal mechanoreceptor.
掲載誌名	正式名：Proceedings of the Japan Academy. Series B, Physical and biological sciences 略　 称：Proc Jpn Acad Ser B Phys Biol Sci ISSNコード：13492896/03862208
掲載区分	国内
巻・号・頁	91(10),pp.560-76
著者・共著者	Tonomura Sotatsu, Ebara Satomi, Bagdasarian Knarik, Uta Daisuke, Ahissar Ehud, Meir Inbal, Lampl Ilan, Kuroda Daichi, Furuta Takahiro, Furue Hidemasa, Kumamoto Kenzo
発行年月	2015
概要	This study focuses on the structure and function of the primary sensory neurons that innervate vibrissal follicles in the rat. Both the peripheral and central terminations, as well as their firing properties were identified using intracellular labelling and recording in trigeminal ganglia in vivo. Fifty-one labelled neurons terminating peripherally, as club-like, Merkel, lanceolate, reticular or spiny endings were identified by their morphology. All neurons responded robustly to air puff stimulation applied to the vibrissal skin. Neurons with club-like endings responded with the highest firing rates; their peripheral processes rarely branched between the cell body and their terminal tips. The central branches of these neurons displayed abundant collaterals terminating within all trigeminal nuclei. Analyses of three-dimensional reconstructions reveal a palisade arrangement of club-like endings bound to the ringwulst by collagen fibers. Our morphological findings suggest that neurons with club-like endings sense mechanical aspects related to the movement of the ringwulst and convey this information to all trigeminal nuclei in the brainstem.
DOI	10.2183/pjab.91.560
PMID	26666306