モリヤ　タクヤ   Takuya Moriya   森谷　卓也    所属   川崎医科大学  医学部 臨床医学　病理学    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Primary non-gestational uterine choriocarcinoma mimicking leiomyoma
掲載誌名	正式名：Pathology international 略　 称：Pathol Int ISSNコード：13205463
掲載区分	国外
巻・号・頁	69(3),pp.160-164
著者・共著者	Sano, R. Moriya, T. Suzuki, S. Saito, W. Shimoya, K. Shiota, M.
発行年月	2019/03
概要	Uterine choriocarcinoma isa trophoblastic neoplasm that is most commonly gestational but can also be non-gestational in origin. However, primary non-gestational uterine choriocarcinoma is very rare, with only few cases having been reported. We report a case of a premenopausal woman who had initially been diagnosed with myoma delivery but who was discovered to have primary non-gestational uterine choriocarcinoma. This 46-year-old woman had no history of pregnancy. She was referred to our hospital for treatment of the myoma delivery. After tumor removal, histological examination led to the diagnosis of choriocarcinoma. The serum human chorionic gonadotropin level (207,300 mIU/mL) prior to surgery was abnormally high, and because the computed tomography scans additionally revealed lung metastasis, the patient was diagnosed with FIGO stage III choriocarcinoma. Due to the lack of pregnancy history and abstinence from sexual intercourse for>1 year, we performed short tandem repeat analysis, and diagnosed the patient with non-gestational choriocarcinoma. Despite treatments using multiple anticancer agents after the surgery, the patient died 1 year after starting the treatments. On this occasion, we report a very rare case of a premenopausal woman who was diagnosed with primary non-gestational uterine choriocarcinoma mimicking leiomayoma.
DOI	10.1111/pin.12763
PMID	30775828