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イシモト ヤスコ
Yasuko Ishimoto
石本 恭子 所属 川崎医療福祉大学 医療技術学部 健康体育学科 職種 准教授 |
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| 論文種別 | 原著 |
| 言語種別 | 英語 |
| 査読の有無 | 査読あり |
| 表題 | A population-based cross-sectional study of the association between periodontitis and arterial stiffness among the older Japanese population. |
| 掲載誌名 | 正式名：Journal of periodontal research 略 称：J Periodontal Res ISSNコード：16000765/00223484 |
| 掲載区分 | 国外 |
| 巻・号・頁 | pp.0-0 |
| 著者・共著者 | Iwasaki Masanori, Kimura Yumi, Yamaga Takayuki, Yamamoto Naomune, Ishikawa Motonao, Wada Taizo, Sakamoto Ryota, Ishimoto Yasuko, Fujisawa Michiko, Okumiya Kiyohito, Otsuka Kuniaki, Matsubayashi Kozo, Ogawa Hiroshi |
| 発行年月 | 2020/12 |
| 概要 | OBJECTIVE:To investigate the potential association between periodontitis and arterial stiffness among the older Japanese population.BACKGROUND:The prevalence of periodontitis is increasing in Japanese older adults. Arterial stiffness increases the risks of cardiovascular events and death, morbidity, and dementia.METHODS:This secondary analysis of data from a cross-sectional study evaluated the periodontal inflamed surface area (PISA), reflecting the amount of inflamed periodontal tissue that was estimated by a full-mouth periodontal examination. Severe periodontitis was defined per the parameters provided by the Centers for Disease Control/American Academy of Periodontology. The Cardio-Ankle Vascular Index (CAVI) was used for measuring the overall stiffness of the artery, and higher CAVI indicated increased arterial stiffness. An ordinal logistic regression model was used to evaluate the association between periodontitis and arterial stiffness.RESULTS:The analysis included 185 Japanese adults [35% men; age, mean (standard deviation) 80.2 (4.4) years]. The average PISA and the prevalence of severe periodontitis were 64.4 mm2 and 27.6%, respectively; 54 (29.2%), 56 (30.3%), and 75 (40.5%) participants were stratified to the CAVI < 9, 9 ≤ CAVI <10, and CAVI ≥ 10 groups, respectively. After adjusting for potential confounders, the odds ratio of the prevalence and severity of arterial stiffness evaluated using CAVI was 1.06 [95% confidence interval (CI) 1.01 to 1.10] for PISA per 10 mm2 and 2.12 (95% CI 1.09 to 4.11) for severe periodontitis.CONCLUSION:Periodontitis was associated with arterial stiffness among Japanese older adults. Further studies are needed to investigate whether arterial stiffness is an intermediate factor in the pathway between periodontitis and systemic diseases, including cardiovascular disease and dementia. |
| DOI | 10.1111/jre.12835 |
| PMID | 33368318 |