フジワラ　アツシ   Atsushi Fujiwara   藤原　篤之    所属   川崎医療福祉大学  リハビリテーション学部 視能療法学科    職種   講師
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Successful resolution of coats disease by photodynamic therapy: a case report.
掲載誌名	正式名：BMC ophthalmology 略　 称：BMC Ophthalmol ISSNコード：14712415/14712415
掲載区分	国外
巻・号・頁	18(1),pp.264
著者・共著者	Namba Michie, Shiode Yusuke, Morizane Yuki, Kimura Shuhei, Hosokawa Mio, Doi Shinichiro, Toshima Shinji, Takahashi Kosuke, Hosogi Mika, Fujiwara Atsushi, Shiraga Fumio
発行年月	2018/10
概要	BACKGROUND:Coats disease is a retinal disease characterized by exudative retinal detachment due to abnormal retinal blood vessels. Coats disease is generally treated using laser photocoagulation and cryotherapy to ablate the abnormal retinal blood vessels. However, if abnormal blood vessels are present near the posterior pole of the eye and there is a severe exudative change there, it is difficult to perform these standard treatments. We describe a case of Coats disease with severe exudative retinal change and retinal vascular abnormality near the posterior pole for which we performed photodynamic therapy and successfully suppressed the disease and improved vision.CASE PRESENTATION:A 15-year-old Japanese boy presented to hospital with a chief complaint of decreased vision in his right eye. At the initial examination, corrected visual acuity of the right eye was 20/100. On the right fundus, exudative retinal detachment with subretinal haemorrhage was observed from the upper intermediate periphery to the posterior pole. Abnormal telangiectatic vessels and microaneurysms were found at the nasal peripheral retina. From these findings, we diagnosed the case as Coats disease. We conducted photodynamic therapy for the right eye. At 10 months after treatment, both the subretinal haemorrhage and the exudative retinal detachment had disappeared completely. Further, the retinal structure of the macula had recovered, and right vision had improved to 20/20.CONCLUSION:Photodynamic therapy may be an effective and safe treatment for Coats disease in cases that present with abnormal retinal vessels close to the posterior pole of the eye.
DOI	10.1186/s12886-018-0930-z
PMID	30309339