モリヤ　タクヤ   Takuya Moriya   森谷　卓也    所属   川崎医科大学  医学部 臨床医学　病理学    職種   教授
論文種別	症例報告
言語種別	英語
査読の有無	査読あり
表題	[A Case Report of Surgery and Chemotherapy for a Patient with Rapidly Progressing Breast Cancer during Pregnancy].
掲載誌名	正式名：Gan to kagaku ryoho. Cancer & chemotherapy 略　 称：Gan To Kagaku Ryoho ISSNコード：03850684/03850684
掲載区分	国外
巻・号・頁	45(5),pp.847-850
著者・共著者	Hazama Yukiko, Nakai Yuichiro, Sugawara Shiori, Nomura Tsunehisa, Matsumoto Keiko, Matsumoto Ryou, Sugihara Mika, Ishida Tsuyoshi, Murata Susumu, Murata Takuya, Nakamura Takafumi, Moriya Takuya, Kurebayashi Junichi, Shimoya Koichiro
発行年月	2018/05
概要	A 33-year-old woman became aware of a right breast mass at her 28th week of pregnancy. From the biopsy results, we diagnosed her with right breast cancer. At her 33rd week of pregnancy, she underwent modified radical mastectomy (pT2N3aM0, Stage III C, ER-negative, PR-negative, HER2-positive), and she elected to receive adjuvant therapy after the surgery during her pregnancy. She received the first course of EC (epirubicin plus cyclophosphamide) therapy on the 13th postoperative day (35 weeks of gestation) and gave a natural, vaginal delivery at 36 weeks and 5 days of gestation. On the 4th day after birth, the patient noticed a contralateral left breast mass and was diagnosed with left breast cancer, after core needle biopsy. She received 4 courses of EC therapy and is currently undergoing PTX plus HER (paclitaxel plus trastuzumab) therapy. Regarding chemotherapy during pregnancy, we recommend that there is no need to perform artificial preterm birth, because chemotherapy has little influence on children after their second-trimester. After the second-trimester, chemotherapy can be safely performed.
PMID	30026449