エンドウ　シュンジ   Shunji Endo   遠藤　俊治    所属   川崎医科大学  医学部 臨床医学　消化器外科学    職種   准教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Motility of the pouch correlates with quality of life after total gastrectomy.
掲載誌名	正式名：Surgery 略　 称：Surgery ISSNコード：00396060/00396060
掲載区分	国外
巻・号・頁	139(4),pp.493-500
著者・共著者	Endo Shunji, Nishida Toshirou, Nishikawa Kazuhiro, Yumiba Takeyoshi, Nakajima Kiyokazu, Yasumasa Keigo, Kitagawa Toru, Ito Toshinori, Matsuda Hikaru
発行年月	2006/04
概要	BACKGROUND:Jejunal pouch reconstruction is used to provide reservoir function after total gastrectomy, but controversy remains regarding pouch functions and quality of life (QOL). In this study, pouch motility was studied in conjunction with postoperative QOL.METHODS:Pouch motility of 23 patients with jejunal pouch interposition after total gastrectomy was examined by manometry under fasting conditions and by an emptying test using dual-scintigraphy under postprandial conditions. Residual food was graded by endoscopic examinations. QOL was evaluated using the Gastrointestinal Quality of Life Index, and a stasis- or dumping-related symptom score.RESULTS:The pouch showed interdigestive contractile activity. Bursts of contractile activity occurred frequently and were long-lasting compared with the migrating motor complex phase III of the control jejunum. The percentage of time of contractile bursts correlated with postprandial pouch emptying (liquid: R(2) = 0.229, P < .03; solid: R(2) = 0.243, P < .02). Patients with little or no residual food had more percentage of time of contractile bursts than those with moderate residual food (P < .01). The percentage of time of contractile bursts was correlated with the Gastrointestinal Quality of Life Index score (R(2) = 0.262, P < .02), stasis-related symptoms (R(2) = 0.279, P < .01), and dumping-related symptoms (R(2) = 0.218, P < .03).CONCLUSIONS:An interposed jejunum pouch showed bursts of contractile activity that affected postoperative gastrointestinal function and patient QOL.
DOI	10.1016/j.surg.2005.08.013
PMID	16627058