フクハラ　トオル   Toru Fukuhara   福原　徹    所属   川崎医科大学  医学部 臨床医学　脳神経外科学２    職種   特任教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Wegener granulomatosis manifesting as meningitis. Case report.
掲載誌名	正式名：J Neurosurg.
掲載区分	国外
巻・号・頁	97(5),pp.1229-1232
著者・共著者	YasuhaharaT,FukuharaToru,NakagawaM,TeraiY,YoshinoK,FujimotoS
担当区分	2nd著者
発行年月	2002/11
概要	The authors describe a unique presentation of Wegener granulomatosis (WG) manifesting predominantly as meningitis. Magnetic resonance imaging demonstrated diffuse meningeal enhancement, including the pia mater, in a 28-year-old man with meningitis. A diagnosis of atypical WG was based on the findings of a dural biopsy sample and an elevated cytoplasmic antineutrophil cytoplasmic antibody (cANCA) titer, although the patient did not have any of the lesions common to WG. Immunosuppressive therapy was quite effective. With treatment, the meningeal enhancement resolved and the cANCA titer normalized. Meningeal granulomatosis as the sole lesion in WG has never been reported in the literature. This atypical course of WG should be noted.