タマダ　ツトム   Tsutomu Tamada   玉田　勉    所属   川崎医科大学  医学部 臨床医学　放射線診断学    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読なし
表題	Hypointense hepatocellular nodules on hepatobiliary phase of Gd-EOB-DTPA-enhanced MRI: Can increasing the flip angle improve conspicuity of lesions?
掲載誌名	正式名：Journal of magnetic resonance imaging : JMRI 略　 称：J Magn Reson Imaging ISSNコード：10531807
巻・号・頁	pp.Epub ahead of print
著者・共著者	Tamada Tsutomu, Ito Katsuyoshi, Yamamoto Akira, Yasokawa Kazuya, Higaki Atsushi, Kanki Akihiko, Sato Tomohiro, Tanimoto Daigo, Higashi Hiroki
担当区分	筆頭著者
発行年月	2012/11
概要	We compared the conspicuity of hypointense hepatocellular nodules in patients with chronic liver disease on hepatobiliary phase (HP) of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) acquired with low to high flip angles (FAs). In all examinations, 96 hepatocellular nodules showing hypointensity on HP were identified. These lesions included 39 hypovascular nodules and 57 hypervascular nodules. Mean CPR and LCS showed the highest value on the 30° FA, followed by 20° and 15° FAs. CPR and LCS of 15° FA were significantly lower than those of 20° and 30° FAs (P < 0.001 to P = 0.007). CPR of 30° FA for hypervascular nodules was significantly greater than that of 20° FA (P < 0.001). In conclusion, in the evaluation of hypointense hepatocellular nodules on HP of Gd-EOB-DTPA-enhanced MRI, higher FA such as 30° should be used rather than low FA such as 15°.