タマダ　ツトム   Tsutomu Tamada   玉田　勉    所属   川崎医科大学  医学部 臨床医学　放射線診断学    職種   教授
論文種別	原著
言語種別	英語
査読の有無	査読あり
表題	Potential clinical factors affecting hepatobiliary enhancement at Gd-EOB-DTPA-enhanced MR imaging.
掲載誌名	正式名：Magn Reson Imaging 略　 称：Magn Reson Imaging
掲載区分	国外
巻・号・頁	30(5),pp.689-693
著者・共著者	Higaki Atsushi, Tamada Tsutomu, Sone Teruki, Kanki Akihiko, Sato Tomohiro, Tanimoto Daigo, Higashi Hiroki, Ito Katsuyoshi
担当区分	2nd著者
発行年月	2012/06
概要	The objective was to clarify the clinical factors that might affect the degree of hepatic parenchymal enhancement at gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging. The presence or absence of chronic liver disease (P=.002), ascites (P=.005) and splenomegaly (P=.027), and the values of prothrombin activity (P=.008), total bilirubin (T-Bil) (P=.001), albumin (P=.001), aspartate aminotransferase (AST) (P=.002) and cholinesterase (P=.007) were significantly correlated with the RE of liver parenchyma at 20 min HP. Among these parameters, increases of T-Bil (P=.011 to .028) and AST (P=.018 to .049) were predictors of decreased hepatic parenchymal enhancement. Hepatic parenchymal enhancement of Gd-EOB-DTPA was affected by various clinical parameters. Impaired hepatobiliary enhancement may be predicted by routine biochemical tests, such as T-Bil and AST.