Faculty Information - Michihiro Okuyama

（Last updated : 2026-04-22 10:07:25）

Michihiro Okuyama
Department Kawasaki Medical School Kawasaki Medical School, Department of Cardiovascular Surgery,

Position Assistant Professor

■ Current specialization

Molecular Biology, Cardiovascular Surgery (Key Word：Vascular Biology, Aorta, Thoracic Aortic Aneurysm, Abdominal Aortic Aneurysm)

■ Journal Articles

1.	2025/10	Adipocyte Calpain-2 Deficiency Reduces Obesity-Accelerated Abdominal Aortic Aneurysm Formation in Mice.
2.	2024/08	Lacticaseibacillus rhamnosus Infective Endocarditis Complicated by Multifocal Mycotic Aneurysms in an Immunocompetent Patient: A Case Report.
3.	2024/08	Surgical Treatment of an Abdominal Aortic Aneurysm in a Patient with a Liver Abscess.
4.	2021/05	Inducible Depletion of Calpain-2 Mitigates Abdominal Aortic Aneurysm in Mice.
5.	2021/05	Vasohibin-2 Aggravates Development of Ascending Aortic Aneurysms but not Abdominal Aortic Aneurysms nor Atherosclerosis in ApoE-Deficient Mice.
6.	2021/04	Mst1/2 Kinases Inhibitor, XMU-MP-1, Attenuates Angiotensin II-Induced Ascending Aortic Expansion in Hypercholesterolemic Mice.
7.	2020/11	Lysyl Oxidase Inhibition Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice.
8.	2019/09	miR-146a Deficiency Accelerates Hepatic Inflammation Without Influencing Diet-induced Obesity in Mice.
9.	2019/04	Exogenous Vasohibin-2 Exacerbates Angiotensin II-Induced Ascending Aortic Dilation in Mice.
10.	2018/12	Diabetic nephropathy is associated with frailty in patients with chronic hemodialysis.
11.	2018/08	Peripheral artery disease is associated with frailty in chronic hemodialysis patients.
12.	2018/04	The Prevalence of Frailty and its Associated Factors in Japanese Hemodialysis Patients.
13.	2016	Chronic Kidney Disease Is Positively and Diabetes Mellitus Is Negatively Associated with Abdominal Aortic Aneurysm.
14.	2015/02	Intracoronary autologous cardiac progenitor cell transfer in patients with hypoplastic left heart syndrome: the TICAP prospective phase 1 controlled trial.
15.	2015	Novel Model of Pulmonary Artery Banding Leading to Right Heart Failure in Rats.
Display 5 items
Display all(15)

■ Presentations

1.	2020/05/01	Inducible Depletion of Calpain-2 Fibrogenic Mesenchymal Cells Attenuates Angiotensin II- induced Abdominal Aortic Aneurysm Formation in Hypercholesterolemic Mice （Speech，General）
2.	2019/05/16	Pharmacological Inhibition of Hippo-YAP Signaling Attenuates Angiotensin II-induced Ascending Aoftic Aneurysms in Male LDL Receptor Deficient Mice （Poster notice，General）
3.	2018/05/10	The Current Patency Rate of Autologous Arteriovenous Fistula in the Snuff-Box and the Risk Factors for its Failure （Poster notice，General）
4.	2017/08/29	Vasohibin-2 exacerbates development of angiotensin II-induced thoracic aortic aneurysms independent of VEGF （Poster notice，General）
5.	2017/05/06	Overexpression of vasohibin-2 exacerbates development of angiotensin II-induced thoracic aortic aneurysms independent of VEGF （Poster notice，General）
6.	2016/05/06	Exogenous Vasohibin-2 Exacerbates Angiotensinn II-induced Ascending Aortic Aneurysms （Poster notice，General）
7.	2014/11/16	Cardiac Magnetic Resonance Late Gadolinium Enhancement is Associated With Ventricular Elastance That May Predict Latent Ventricular Dysfunction After Fontan Procedure （Poster notice，General）
8.	2014/08/31	Engineering bioartificial heart by human stem cells with perfusion-decellularized three-dimensional matrix materials （Poster notice，General）
9.	2014/07/15	Late Gadolinium Enhancement on Cardiac MRI Identifies Ventricular Dysfunction and Regional Myocardial Dyssynchrony in Patients with Univentricular Heart Diseases （Poster notice，General）
Display 5 items
Display all(9)

■ Awards

2018/09

Saha Cardiovascular Research Center, 21st Gill Heart Institute Cardiovascular Research Day Outstanding Postdoctoral Fellow Poster Presentation- 2nd Place, 21st Gill Heart Institute Cardiovascular Research Day (Inhibition of Hippo-YAP Signaling Does Not Affect Angiotensin II-induced Abdominal Aortic Aneurysms in Male LDL Receptor Deficient Mice.)