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Current specialization
Journal Articles
Presentations
（Last updated : 2026-08-04 10:01:42）
Hiroyuki Kadoya
Department
Kawasaki Medical School Kawasaki Medical School, Department of General Geriatric Medicine,
Position
Associate Professor
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Current specialization
Nephrology
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Journal Articles
1.
2026/07/13
Sequential Management Enabling Continuation of Peritoneal Dialysis in Autosomal Dominant Polycystic Kidney Disease Despite Multiple Complications
2.
2026/07
Advancing Geriatric Care in Japan: Integrating the 5Ms Framework With Comprehensive Geriatric Assessment for Enhanced Clinical Practice in a Super-Aged Society
3.
2026/04
Finerenone Improves Albuminuria via MR-TRPC Signaling in Diabetic Kidney Disease
4.
2026/01
Survey of exit-site management practices of peritoneal dialysis in Japan
5.
2026
Unexpected drainage failure in a patient receiving long-term peritoneal dialysis.
6.
2025/12/17
The Antibiotic effect of Silver CAPD Catheter on Peritoneal Dialysis-related infections (ASCA-PD) study: a multicenter randomized open-label trial protocol.
7.
2025/04/30
A case of advanced renal cell carcinoma with concomitant development of multiple endocrine neoplasia type 1 that affected treatment progress with immunotherapy
8.
2024/11/02
ASK-1 activation exacerbates kidney dysfunction via increment of glomerular permeability and accelerates cellular aging in diabetic kidney disease model mice
9.
2024/11
Effects of Beraprost on Intestinal Microcirculation and Barrier Function in a Mouse Model of Renal Failure. inpress
10.
2024/09
Evaluation of glomerular hemodynamic changes by sodium-glucose-transporter 2 inhibition in type 2 diabetic rats using in vivo imaging
11.
2024/09
Treatment of chronic kidney disease in older populations
12.
2024/08
Never give up! A case of weaning from 40 years of hemodialysis
13.
2024/04/10
Neuronally differentiated macula densa cells regulate tissue remodeling and regeneration in the kidney
14.
2023/12/19
IL-1β may be an indicator of peritoneal deterioration after healing of peritoneal dialysis-associated peritonitis
15.
2023/10/01
Insights into the regulation of glomerular filtration rate by the Keap1-Nrf2 pathway
16.
2023/09
Activation of the inflammasome drives peritoneal deterioration in a mouse model of peritoneal fibrosis
17.
2022/03/23
A case of pleuroperitoneal communication during long-term steroid therapy for dermatomyositis
18.
2021/11
Dipeptidyl peptidase-4 inhibitor linagliptin reduces urinary albumin excretion through the protection of glomerular endothelial function
19.
2021/08
A rare case of amyloid light-chain amyloidosis with bilateral perirenal hematoma shortly after initiation of peritoneal dialysis.
20.
2021/06/04
Dual disruption of eNOS and ApoE gene accelerates kidney fibrosis and senescence after injury
21.
2021/06
Renal cell carcinoma sharply captured by imaging technology at an early stage in a hemodialysis patient: Usefulness of noninvasive monochrome superb microvascular imaging
22.
2021/05/24
Serial intravital imaging captures dynamic and functional endothelial remodeling with single-cell resolution
23.
2021/05/11
Effect of zinc deficiency on chronic kidney disease progression and effect modification by hypoalbuminemia.
24.
2021/01/20
Roxadustat and thyroid-stimulating hormone suppression.
25.
2020/12/24
Drastic change in protein intake may cause a rapid decline of residual renal function after initiation of peritoneal dialysis.
26.
2020/11/01
Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in InsAkita diabetic mice.
27.
2020/10/02
Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis
28.
2020/05/01
Klotho is a novel therapeutic target in peritoneal fibrosis via Wnt signaling inhibition.
29.
2019/01
Aldosterone induces albuminuria via matrix metalloproteinase–dependent damage of the endothelial glycocalyx
30.
2018/01
Advances in Renal Cell Imaging
31.
2017/05/02
Colchicine attenuates renal fibrosis in a murine unilateral ureteral obstruction model.
32.
2017/03
Tracking the stochastic fate of cells of the renin lineage after podocyte depletion using multicolor reporters and intravital imaging.
33.
2016/10
Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.
34.
2016/08
A Case of Copper Deficiency-Induced Pancytopenia With Maintenance Hemodialysis Outpatient Treated With Polaprezinc.
35.
2016/02
Prevalence of gastroesophageal reflux disease symptoms and effects of esomeprazole on the quality of life related to reflux and dyspepsia in patients on maintenance hemodialysis.
36.
2015/09
Excess aldosterone is a critical danger signal for inflammasome activation in the development of renal fibrosis in mice.
37.
2015/08
Deficiency of endothelial nitric oxide signaling pathway exacerbates peritoneal fibrosis in mice.
38.
2015/06/05
Combination Irbesartan/Amlodipine versus Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin-Induced Diabetic Nephropathy.
39.
2015/05
Combination Irbesartan/Amlodipine versus Irbesartan/Cilnidipine for
Attenuation of Albuminuria in Rats with Streptozotocin-Induced Diabetic
Nephropathy
40.
2014
Hypertension promotes islet morphological changes with vascular injury on pre-diabetic status in SHRsp rats.
41.
2013/04
Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status.
42.
2012/05
A case of anti-GBM glomerulonephritis and membranous nephropathy in a patient with primary biliary cirrhosis
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Presentations
1.
2026/03/29
Survey of exit-site management practices of peritoneal dialysis in Japan （Poster notice，General）
2.
2024/09/15
Endothelial Dysfunction Fuels Progression from Acute to Chronic Kidney Disease through Macrophage-Mediated β-Catenin Activation （Poster notice，General）
3.
2024/09/15
Impaired Glomerular Epithelial Cell sGC Activation Promotes Glomer- Significance of Glomerular Epithelial Cell sGC Activation via eNOS-NO Pathway in Diabetic Kidney Disease （Poster notice，General）
4.
2024/09/15
SGLT2 Inhibition suppresses residual nephron glomerular hyperfiltration in Non-Diabetic Chronic Kidney Disease （Poster notice，General）
5.
2024/09/14
Elucidation of glomerular hemodynamic changes by mineralocorticoid receptor blocker esaxerenone in diabetic kidney disease （Poster notice，General）
6.
2022/10/15
Endothelial dysfunction exacerbates kidney dysfunction in ageing kidney via activation of inflammasome （Poster notice，General）
7.
2022/10/15
eNOS-NO pathway regulates inflammasome activation in diabetic mice via modulation of CEBP translocation （Poster notice，General）
8.
2022/10/15
eNOS/NO signaling regulates renal interstitial fibrosis by increasing cytoplasmic beta-catenin degradation （Poster notice，General）
9.
2022/10/15
Regulatory mechanism of glomerular filtration rate by the Keap1/Nrf2 pathway （Poster notice，General）
10.
2021/02/28
Evaluation of glomerular hemodynamic changes by SGLT2 inhibitor and ARB in type 2 diabetic rats using in vivo imaging （Speech，General）
11.
2020/10/19
Effect of Zinc Deficiency on CKD Progression and Effect Modification by Hypoalbuminemia. （Poster notice，General）
12.
2020/10/19
eNOS/NO Signaling Attenuates Progression of Age-Related Kidney Diseases via Suppression of Inflammasome. （Poster notice，General）
13.
2020/10/02
DEFICIENT OF ENOS/NO PATHWAY PROMOTES AKI TO CKD TRANSITION AFTER ISCHEMIC REPERFUSION （Poster notice，General）
14.
2020/10/02
ENOS/NO SIGNALLING ATTENUATES GLOMERULAR INJURY IN DIABETIC MICE VIA SUPPRESSION OF INFLAMMASOME ACTIVATION （Poster notice，General）
15.
2020/10/02
EVALUATION OF THE MECHANISM OF GLOMERULAR ARTERIOLE CHANGES BY SGLT2 INHIBITION IN TYPE 2 DIABETIC RATS （Poster notice，General）
16.
2020/10/02
Inflammasome Activation Plays a Key Role on the Progression of Peritoneal Fibrosis in Mice （Poster notice，General）
17.
2020/06/07
Effects of sodium–glucose cotransporter 2 inhibitor, canagliflozin on glomerular hyperfiltration and oxidative stress in mice with type 2 diabetes （Speech，General）
18.
2020/06/07
EVALUATION OF GLOMERULAR HEMODYNAMIC CHANGES BY SGLT2 INHIBITION IN TYPE 2 DIABETIC RATS USING IN VIVO IMAGING TECHNIQUES （Speech，General）
19.
2020/02/15
Zinc deficiency is a risk factor for chronic kidney disease progression （Speech，General）
20.
2019/11/09
Endothelial Nitric Oxide Synthase/Nitric Oxide Pathway Underlies the Mechanisms of AKI to CKD Transition via Prolonged Activation of the Wnt/β-Catenin Pathway （Poster notice，General）
21.
2019/11/09
Implication of Inflammasome Activation in the Progression of Peritoneal Fibrosis in Mice （Poster notice，General）
22.
2019/11/08
Clarification of the Mechanism of Acute GFR Change by SGLT2 Inhibition with In Vivo Imaging Technique （Poster notice，General）
23.
2019/09/07
A Case of rapid decline of residual renal function after initiation of initiation of peritoneal dialysis. （Poster notice，General）
24.
2019/09/05
Inframmasome activation plays a key role in chronic inflammation and development of peri-toneal fibrosis （Poster notice，General）
25.
2019/06/13
Implication of inflammasome activation in the development of peritoneal fibrosis. （Poster notice，General）
26.
2018/10/25
Endothelial Dysfunction Exacerbates Renal Tubular Cell Injury Through Inflammasome Activation in a Hypertensive Mouse Model （Poster notice，General）
27.
2018/10/25
Uremic Toxin Decreases Intestinal Defense Peptides and Barrier Functions in Chronic Renal Failure Mice （Poster notice，General）
28.
2018/02/22
A case of copper deficiency-induced pancytopenia with maintenance hemodialysis outpatient treated with polaprezinc . （Poster notice，General）
29.
2016/09/26
Hypertension Promotes Islet Morphological Changes with Vascular Injury on Prediabetic Status in SHR-SP Rats. （Poster notice，General）
30.
2015/11/05
Possible Implication of Xanthine Oxidase Activation on the Pathogenesis Diabetic Nephropathy. （Poster notice，General）
31.
2015/09/28
Excess Aldosterone is a Critical Danger Signal for Inflammasome Activation in the Development of Renal Fibrosis in Mice. （Poster notice，General）
32.
2015/09/25
Possible implication of xanthine oxidase activation on the pathogenesis diabetic nephropathy. （Poster notice，General）
33.
2015/09/25
Visualization of in vivo renin activity and its application to study the pathogenetic mechanisms of diabetic nephropathy （Poster notice，General）
34.
2015/03/16
Low-Dose Colchicine Treatment Attenuates Renal Fibrosis in Mice Unilateral Ureteral Obstruction. （Poster notice，General）
35.
2015/02/28
Protective role of klotho protein on peritoneal membrane via suppression of wnt/B-catenin signaling in mice. （Speech，General）
36.
2014/11/15
Klotho Overexpression Attenuates Peritoneal Fibrosis via Suppression of Wnt/B-Catenin Signaling Pathway in Mice （Speech，General）
37.
2014/11/14
Enhancement of Wnt/B-Catenin Signaling Promotes Renal Fibrosis by Inducing Cell Cycle Arrest at the G2/M Phase in Tubular Epithelial Cells （Poster notice，General）
38.
2014/10/17
Development of a Novel In Vivo-Imaging Technique to Detect Renin-Activity in an Attempt to Elucidate Reno-Protective Effects of Calcium-Channel Blocker （Poster notice，General）
39.
2014/10/17
Molecular Mechanisms of Aldosterone-Induced Renal Interstitial Fibrosis and Ameliorative Effects of Mineralocorticoid Receptor Antagonist （Speech，General）
40.
2014/06/01
Activation of eNOS Signaling Attenuates Renal Fibrosis in Mice by The Increase of Beta Catenin Degradation. （Poster notice，General）
41.
2014/05/15
Implication of Inflammasome Activation in The Development of Renal Interstitial Inflammation and Fibrosis Induced by Aldosterone. （Speech，General）
42.
2014/02/22
Aldosterone induces renal tubulointerstitial inflammation and fibrosis via activation of inflammasome in infltrating macrophages. （Poster notice，General）
43.
2013/12/17
Implication of inflammasome activation in the development of renal interstitial inflammation and fibrosis induced by aldosterone. （Speech，General）
44.
2013/11/09
Comparison of Combination Therapy with Irbesartan/Amlodipine and Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin-Induced Diabetic Nephropathy. （Poster notice，General）
45.
2013/11/07
Implication of Inflammasome Activation via Mitochondrial Reactive Oxygen Species in the Development of Renal Interstitial Fibrosis Induced by Aldosterone. （Poster notice，General）
46.
2013/11/07
T Type Ca-Channel Blocker Exerts Anti-Albuminuic Effect through Amelioration of eNOS Uncoupling in Hypertensive Kidney Disease Model. （Poster notice，General）
47.
2013/10/26
Molecular Mechanism of Mineralocorticoid Receptor Antagonist on Suppressive Effects of Inflammasome Activation by Aldosterone. （Poster notice，General）
48.
2013/10/24
Comparison of Combination Therapy with Irbesartan/Amlodipine and Irbesartan/Cilnidipine for Attenuation of Albuminuria in Rats with Streptozotocin Induced Diabetic Nephropathy. （Poster notice，General）
49.
2013/10/24
Investigation for the Mechanisms of Anti-albuminuic Effects of T Type Ca-channel Blocker through Amelioration of eNOS Uncoupling. （Speech，General）
50.
2013/10/24
Islet Microangiopathy in Hypertensive Rats and the Protective Effects of ARB on the Islet Morphology. （Speech，General）
51.
2013/06/02
Implications of Inflammasome-Activation in Macrophage on the Development of Renal Interstitial Inflammation and Fibrosis in Mice. （Poster notice，General）
52.
2013/06/01
Development of Novel Technique to Visualize in vivo Renin Activity and Analysis of Reno-Protective Actions of Renin Inhibitor in Diabetic Nephropathy. （Poster notice，General）
53.
2013/06/01
Rosuvastatin Maintain Glomerular Endothelial Surface layer Through Nrf2 Activation in Mouse Diabetic Nephropathy. （Poster notice，General）
54.
2013/04/28
Aldosterone induces renal interstitial inflammation and fibrosis by activation of inflammasome via mitochondrial reactive oxygen species in macrophage. （Poster notice，General）
55.
2013/04/21
Implication of inflammasome in the development of renal interstitial fibrosis induced by aldsoterone （Poster notice，General）
56.
2012/11/06
Spironolactone Suppresses the Inflammasome in Aldosterone Induced Renal Dysfunction via Blood Pressure Independent Pathway. （Poster notice，General）
57.
2012/11/02
Erythropoietin Activates NAD(P)H Oxidase via Erythropoietin Receptor and Beta Common Receptor on Vascular Endothelial Cells. （Poster notice，General）
58.
2012/11/02
Klotho Attenuates Inflammation of Adipose Tissue and Development of Insulin Resistance in High-Fat Induced Obese Mice. （Poster notice，General）
59.
2012/11/02
Stimulation of Soluble Guanylate Cyclase Attenuates Epithelial-Mesenchymal Transition of the Peritoneal Membrane and Prevent the Development of Peritoneal Fibrosis. （Speech，General）
60.
2012/07/20
eNOS-sGC pathway suppresses renal fibrosis via interruption of the Wnt-beta-catenin pathway in UUO mice. （Poster notice，General）
61.
2012/05/25
Endothelial Dysfunction promotes the Transition from Compensatory Renal Hypertrophy to Kidney Injury after Unilateral Neophrectomy in Mice. （Poster notice）
62.
2012/05/25
Preservation of Endothelial GTP Cyclohydrolase I Activity and Improvement of Renal Nitric Oxide Availability Prevent the Development of Diabetic Nephropathy （Poster notice，General）
63.
2011/11/12
Low-Dose Erythropoietin Increases Superoxide Production in Normal Rat Aorta and Endothelial Cells （Poster notice，General）
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