Faculty Information - Ryo Shirai

（Last updated : 2026-01-30 14:32:27）

Ryo Shirai
Department Kawasaki Medical School Kawasaki Medical School, Department of General Internal Medicine 1,

Position Associate Professor

■ Journal

1.	2025/10	Deep Neck Infection Caused by Pseudomonas aeruginosa.
2.	2022/05/31	Massive Hemoptysis From a Spontaneously Regression Inflammatory Bronchial Polyp.
3.	2022	A Patient With Neuroleptic Malignant Syndrome, Water Intoxication and Hyponatremia Associated With Severe Cerebral Edema and Coma.
4.	2022	Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment.
5.	2022	Use of endobronchial Watanabe spigot and coagulation factor XIII supplementation in the treatment of persistent pneumothorax due to pneumocystis pneumonia with human immunodeficiency virus infection.
6.	2018/12	Biomarkers for differentiation of patients with asthma and chronic obstractive pulmonary disease
7.	2018/05	Evaluation of Bioequivalence Between the New Procaterol Hydrochloride Hydrate Dry Powder Inhaler and the Approved Dry Powder Inhaler in PatientsWith Asthma in a Randomized, Double-Blind, Double-Dummy,Crossover Comparison Study:A Phase 3 Study
8.	2013/02	A Clinical Study on Bacteroides fagilis Bacteremia
9.	2012/09	Cloning of the lanosterol 14-alpha-demethylase ( ERG11 ) gene in Trichosporon asahii: a possible association between G453R amino acid substitution and azole resistance in T. asahii
10.	2012/03	Inhibitory effect of statins on inflammatory cytokine production from human bronchial epithelial cells.
11.	2011/07	Clinical features of healthcare-associated pneumonia (HCAP) in a Japanese community hospital: comparisons among nursing home-acquired pneumonia (NHAP), HCAP other than NHAP, and community-acquired pneumonia.
12.	2010	A retrospective study of the patients with positive ImmunoCard Mycoplasma test on an outpatient clinic basis.
13.	2010	Low expression of T-cell co-stimulatory molecules in bone marrow-derived dendritic cells in a mouse model of chronic respiratory infection with Pseudomonas aeruginosa.
14.	2007	Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.
15.	2006	Elevated levels of interferon gamma-inducible protein-10 and epithelial neutrophil-activating peptide-78 in patients with pulmonary sarcoidosis.
16.	2004	Effect of erythromycin on chronic respiratory infection caused by Pseudomonas aeruginosa with biofilm formation in an experimental murine model.
17.	2003	Cytokine and surface receptor diversity of NK cells in resistant C3H/HeN and susceptible BALB/c mice with chronic Pseudomonas aeruginosa lung infection.
18.	1999	Immunological function and nutritional status in patients with hepatocellular carcinoma.
19.	1999	Reduced immune function and malnutrition in the elderly.
20.	1998/11	Immunological competence and nutritional status in patients with lung cancer.
21.	1997/07	Protective effect of granulocyte colony-stimulating factor (G-CSF) in a granulocytopenic mouse model of Pseudomonas aeruginosa lung infection through enhanced phagocytosis and killing by alveolar macrophages through priming tumour necrosis factor-alpha (TNF-alpha) production.
22.	1997	Analysis of T cell subsets and beta chemokines in patients with pulmonary sarcoidosis.
23.	1997	Phenotypic characterization of T cells in bronchoalveolar lavage fluid (BALF) and peripheral blood of patients with diffuse panbronchiolitis; the importance of cytotoxic T cells.
24.	1997	Species-specific B-cell epitope on the C-terminal region of the alpha antigen from Mycobacterium scrofulaceum
25.	1996	Inhibitory effect of erythromycin on interleukin 8 production by 1 alpha,25-dihydroxyvitamin D3-stimulated THP-1 cells
26.	1996	Interleukin 1 beta, tumor necrosis factor alpha, and interleukin 8 in bronchoalveolar lavage fluid of patients with diffuse panbronchiolitis: a potential mechanism of macrolide therapy.
27.	1996	Significance of IL-1beta and IL-1 receptor antagonist (IL-1Ra) in bronchoalveolar lavage fluid (BALF) in patients with diffuse panbronchiolitis (DPB)
28.	1995	Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection.
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