Faculty Information - Hiroyuki Kamao

（Last updated : 2026-09-07 12:14:51）

Hiroyuki Kamao
Department Kawasaki Medical School Kawasaki Medical School, Department of Ophthalmology 1,

Position Associate Professor

■ Journal Articles

1.	2026/07/30	Noninfectious intraocular inflammation with hypopyon after intravitreal aflibercept 8 mg injection for neovascular age-related macular degeneration: a case report
2.	2026/07/28	Association of Vortex Vein Morphology with Punctate Hyperfluorescence on ICGA in Neovascular Age-Related Macular Degeneration
3.	2026/04/09	Five-Year Changes in Pachydrusen with Late-Phase Hyperfluorescence on Indocyanine Green Angiography.
4.	2025/12/04	Clinical Characteristics of Patients with Neovascular Age-Related Macular Degeneration and Responses to Anti-VEGF Therapy: Four-Group Stratification Based on Drusen and Punctate Hyperfluorescence
5.	2025/09/20	Impact of Punctate Hyperfluorescence Status on Treatment Outcomes of Faricimab Versus Aflibercept in Neovascular Age-Related Macular Degeneration
6.	2025/07/19	Punctate Hyperfluorescence as a Favorable Predictive Factor for Treatment Response Following a Switch to Brolucizumab for Patients with Aflibercept-Refractory Neovascular Age-Related Macular Degeneration
7.	2025/02/21	Treatment Outcomes of Simple and Complex Central Serous Chorioretinopathy.
8.	2024/09/30	Graft survival of major histocompatibility complex deficient stem cell-derived retinal cells
9.	2024/09/12	Clinical Characteristics of Punctate Hyperfluorescence Spots in the Fellow Eye of Patients with Unilateral Macular Neovascularization with No Drusen.
10.	2024/06/27	Clinical characteristics of unilateral macular neovascularization patients with pachydrusen in the fellow eye.
11.	2024/01/30	The Effect of a Loading Dose Regimen in the Switch to Brolucizumab for Patients with Aflibercept-Resistant nAMD
12.	2021/04/27	Clinical characteristics of neovascular age-related macular degeneration without typical drusen
13.	2021/03/22	A ROCK inhibitor promotes graft survival during transplantation of iPS-cell-derived retinal cells
14.	2021/01	Immunological aspects of RPE cell transplantation
15.	2020	A strategy for personalized treatment of iPS-retinal immune rejections assessed in cynomolgus monkey models.
16.	2019/06	ROCK inhibitor-induced promotion of retinal pigment epithelial cell motility during wound healing
17.	2019/04	Mycoplasma ocular infection in subretinal graft transplantation of iPS cells-derived retinal pigment epithelial cells
18.	2019/03	Evaluation of retinal pigment epithelial cell cytotoxicity of recombinant tissue plasminogen activator using human-induced pluripotent stem cells
19.	2018/11	Effects of smoking on outcomes of antivascular endothelial growth factor therapy in patients with neovascular age-related macular degeneration smoking and anti-VEGF therapy in nAMD.
20.	2017/03	Autologous induced stem-cell-derived retina cells for macular degeneration
21.	2017/01	Evaluation of the surgical device and procedure for extracellular matrix-scaffold-supported human iPSC-derived retinal pigment epithelium cell sheet transplantation.
22.	2017	Detection of retinal pigment epithelium-specific antibody in iPSC-derived retinal pigment epithelium transplantation models
23.	2016/10	Successful transplantation of retinal pigment epithelial cells from MHC homozygote iPSCs in MHC-matched models
24.	2015/05	Protective effects of human iPS-derived retinal pigmented epithelial cells in comparison with human mesenchymal stromal cells and human neural stem cells on the degenerating retina in rd1 mice
25.	2015/01	Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
26.	2015	Intravitreal recombinant tissue plasminogen activator without gas injection in a patient with massive submacular hemorrhage associated with age-related macular degeneration: A case report
27.	2014/11	Objective evaluation of the degree of pigmentation in human induced pluripotent stem cell-derived RPE.
28.	2014/02	Characterization of human induced pluripotent stem cell-derived retinal pigment epithelium cell sheets aiming for clinical application
29.	2014/01	Tumorigenicity studies of induced pluripotent stem cell (iPSC)-derived retinal pigment epithelium (RPE) for the treatment of age-related macular degeneration
30.	2013/12	Generation of retinal pigment epithelium from human induced pluripotent stem cells showed polarized secretion of VEGF and PEDF
31.	2013/08	Pigment epithelium-derived factor secreted from retinal pigment epithelium facilitates apoptotic cell death of iPSC
32.	2013/01	A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration
33.	2013	induced pluripotent stem cells derived retinal pigment epithlium cell-sheets for clinical transplantation
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■ Presentations

1.	2023/10/06	Selective Degeneration of Retinal Photoreceptor Cell in Prosaposin Transgenic Mice （Speech，General）
2.	2023/07/06	Degeneration of Retinal Photoreceptor Cell in Prosaposin Transgenic Mice （Poster notice，General）
3.	2018/05/02	Rock inhibitor-induced enhancement of retinal pigment epithelial cell adhesion. （Poster notice，General）
4.	2014/05/08	Protective effects of human iPS-derived retinal pigmented epithelial cells in comparison with human mesenchymal stromal cells and human neural stem cells on the degenerating retina in rd1 mice （Poster notice，General）
5.	2014/05/05	Evaluation of Degree of Pigmentation as an Indicator of Maturation status in Human iPSC-RPE （Poster notice，General）
6.	2014/04/02	Comparison of imaging in gas-filled eyes using swept-source optical coherence tomography and spectral-domain optical coherence tomography （Poster notice，General）
7.	2014/04/02	Development of a novel device and surgery for human iPSC-RPE Cell-Sheet transplantation （Poster notice，General）
8.	2013/05/10	Development of a novel device and surgery for subretinal transplantation of human iPSC-RPE cell-sheet （Poster notice，General）
9.	2012/06/12	induced Pluliptent Stem Cells-Derived Retinal Pigemnet Epithelial Cell Sheets For Clinical Therapy （Speech，General）
10.	2012/05/10	Gene Expression and Immunogenicity of induced Pluliptent Stem Cells-Derived Retinal Pigemnet Epithelial Cells （Poster notice，General）
11.	2012/05/06	A prototype Instrument for subretinal transplantation of induced pluripotent stem (iPS) cell-derived retinal pigment epithelial cell sheets. （Poster notice，General）
12.	2012/02/28	Characterization of iPSC-derived retinal pigment epithelial cell sheets for clinical therapy （Speech，General）
13.	2012/02/16	Gene Expression and Immunogenicity of induced Pluliptent Stem Cells-Derived Retinal Pigemnet Epithelial Cells （Poster notice，General）
14.	2011/12/03	A prototype instrument for subretinal transplantation of retinal pigment epithelial cell sheets.
15.	2011/09/13	Immunogenicity of induced pluripotent stem cells-derived retinal pigment epithelial cells （Speech，General）
16.	2011/05/04	Manipulation of cell sheets with the pneumatic balloon actuator. （General）
17.	2011/05/04	Preparation of iPS-derived RPE sheets for transplantation therapy （Poster notice，General）
18.	2010/05/03	Induction of RPE Cells From Monkey iPS Cells （Poster notice，General）
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■ Awards

2016/04

Japanese Ophthalmological Society Japanese Ophthalmological Society Young Investigator's Award (Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application)

■ Acquisition patent

METHOD OF PRODUCING RETINAL PIGMENT EPITHELIAL CELL SHEET