(Last updated : 2025-11-01 11:41:15)
  Nagio Takigawa
   Department   Kawasaki Medical School  Kawasaki Medical School, Department of General Internal Medicine 4,
   Position   Professor
■ Current specialization
Respiratory medicine, Molecular biology, General internal medicine (Key Word:drug resistance, molecular target, chemotherapy, immunotherapy) 
■ Publications
1. 2015/08   Cancer Stem Cells and Chemoresistance, Stem Cells in Modeling Human Genetic Diseases 
2. 2011/09   “Hairy morphology” of hairy cell leukemia-Japanese variant may disappear under specific conditions, BloodMed 
■ Journal Articles
1. 2025/11 Impact of antibiotic use on survival in patients with advanced non-small cell lung cancer treated with immune checkpoint inhibitor and chemotherapy 
2. 2025/10/16 Acute Radiation Esophagitis After Chemoradiotherapy Demonstrating "Tube-Like" FDG Uptake on PET-CT: Case Report and Literature Review 
3. 2025/09/08 Lazertinib: A Cardio-Safer Alternative to Osimertinib for Epidermal Growth Factor Receptor L858R/T790M Double-Mutant Tyrosine Kinase Resistant Non-Small Cell Lung Cancer 
4. 2025/08/01 Influence of Primary Care Physicians on End-of-Life Treatment Choices in Lung Cancer Diagnosed in the Emergency Department. 
5. 2025/07/28 Utility of ultrasound-guided transbronchial needle biopsy using an acquire needle in the diagnosis of chest and mediastinal diseases 
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■ Presentations
1. 2023/10/11 A novel molecular target, superoxide dismutase 1, in ALK inhibitor-resistant lung cancer cells, detected through proteomic analysis (Poster notice,General) 
2. 2019/09 A randomized trial of sodium alginate prevention of radiation-induced esophagitis in patients with locally advanced NSCLC receiving concurrent chemoradiotherapy: OLCSG1401 (Poster notice) 
3. 2019/04/02 Development of an integrated CRISPR interference system targeting Np63 to treat lung and esophageal squamous cell carcinoma. (Poster notice,General) 
4. 2018/09/28 Targeted silencing of SOX2 by an ATF showed antitumor effect in lung and esophageal squamous cell carcinoma (Poster notice) 
5. 2018/07/20 Patients with osteosarcoma and soft tissue sarcoma tend to become cancer refugees in
Japanese regional cities (Poster notice) 
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