Faculty Information - Munenori Takaoka

（Last updated : 2024-09-04 09:11:48）

Munenori Takaoka
Department Kawasaki Medical School Kawasaki Medical School, Department of General Surgery,

Position Associate Professor

■ Journal

1.	2017/11	Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma.
2.	2017/10	Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma.
3.	2017/04	False-Positive Cases of Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomographic Scans in Metastasis of Esophageal Cancer
4.	2017/02	A Case of Cholesterol Crystal Embolization with Hemorrhagic Imntestinal Ulcer
5.	2017/02	Evaluation of intra-ductal cancer spread using contrast superb micro-vascular imaging(SMI)-a case report-
6.	2015/06	Skin Tube Reconstruction for Esophageal Defects due to Postoperative Complications: Applying a skin flap in esophageal resection and reconstruction
7.	2015/06	TAE226,a Bis-Anilio Pyrimidine Compound,Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells
8.	2015/05	Feasibility of oral administration of S-1 as adjuvant chemotherapy in gastric cancer: 4-week S-1 administration followed by 2-week rest vs. 2-week administration followed by 1-week rest
9.	2014/12	A case report of isolated presacral squamous cell carcinoma developd four years after gastrectomy
10.	2014/12	Amino acid signaling in the intestine: The roles of glutamine, leucine and arginine
11.	2013/11	Gastric function preserving esophagectomy for esophageal cancer
12.	2013/08	Inhibition of the Growth Factor MDK/Midkine by a Novel Small Molecule Compound to Treat Non-Small Cell Lung Cancers
13.	2013/01	Antiproliferative effect of a novel mTOR inhibitor temsirolimus contributes to the prolonged survival of orthotopic esophageal cancer-bearing mice.
14.	2013/01	Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer
15.	2012/12	A case of cecal volvulus in a cerebral palsy patient: Usefulness of multidetector computed tomography for preoperative diagnosis
16.	2012/11	Anti-tumor effect of a novel FAK inhibitor TAE226 against human oral squamous cell carcinoma.
17.	2012/09	Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer.
18.	2012/08	Jejunal interposition reconstruction with a stomach preserving esophagectomy improves postoperative weight loss and reflux symptoms for esophageal cancer patients.
19.	2012/07	Esophageal cancer exhibits resistance to a novel IGF-1R inhibitor NVP-AEW541 with maintained RAS-MAPK activity.
20.	2012/07	Giant gastrointestinal stromal tumor of the jejunum resected after treatmentwith imatinib
21.	2012/07	Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer.
22.	2012/04	Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer.
23.	2010/09	Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.
24.	2010/07	HSP90 and its inhibitors.
25.	2010/04	Can it become a potential therapeutic target?
26.	2010/04	RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer.
27.	2010/02	The establishment of a new mouse model with orthotopic esophageal cancer showing the esophageal stricture.
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■ Presentation

1.	2018/09/28	Targeted silencing of SOX2 by an ATF showed antitumor effect in lung and esophageal squamous cell carcinoma （Poster notice）
2.	2018/09/16	False positive cases of FDG-PET/CT in metastasis of esophageal squamous cell carcinoma （Poster notice）
3.	2018/09/05	Lymph node metastasis in middle and lower bile duct cancer:Prognostic impact and distribution （Poster notice，General）
4.	2018/06/08	A surgical case of jejunal aberrant pancreas containing high-grade pancreatic intraepithelial neoplasia(PanIN3) （Poster notice，General）
5.	2018/06/08	Remnant pancreatic resection for pancreatic cancer （Poster notice，General）
6.	2018/04/16	Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma （Poster notice，General）
7.	2017/06/14	Laparocopic ventral hernia repair with fascial defect closure （Poster notice，General）
8.	2017/06/09	A surgical case of metachronous liver metastasis of hepatoid adenocarcinoma of the stomach （Poster notice，General）
9.	2017/06/08	Prognostic factors for resected adenocarcinomas of the ampulla of vater （Poster notice，General）
10.	2017/04/03	Development of a novel targeted therapy for malignant mesothelioma carcinoma by a midkine inhibitor. （Poster notice）
11.	2016/10/06	SOX2 suppresses CDKN1A to sustain growth of lung squamous cell carcinoma （Speech，General）
12.	2016/06/15	Suturing Techniques for Closure of Fascial Defect during Laparoscopic Ventral Hernia Repairs:a review of the literature （Poster notice）
13.	2016/04/18	Sox2 silencing upregulates CDKNIA and suppresses growth of lung squamous cell carcinoma （Poster notice）
14.	2016/03/17	Minilaparoscopic inguinal hernia repair(m-TAPP)with 5mm laparoscope and 2mm grasper:An alternative to traditional TAPP （Poster notice）
15.	2015/06/03	Micro-laparoscopic Inguinal Hernia Repair (M-Tapp): An Alternative to Traditional Tapp （Poster notice，General）
16.	2015/04/21	Developmemt of a Sox2 targeting therapy for the treatment of lung squamous cell carcinoma （Poster notice，General）
17.	2015/04/20	Esphageal cancer exhibits a resistance to the chemical of IGF-1R with a maintained Ras-MAPK activity （Poster notice，General）
18.	2015/03/18	Remnant pancreatic resection for pancreatic cancer （Poster notice，General）
19.	2014/09/27	Sox2 silencing suppresses cell growth and colony formation of squamous cell lung cancer （Poster notice，Panelist at Symposium/Workshop (Applied)）
20.	2014/06/26	TAPP USING NEEDLESCOPIC INSTRUMENTS FOR INGUINAL HERNIA IN ADULTS. （Poster notice，General）
21.	2014/04/06	Effective use of MDK/Midkine and MEK inhibitor to treat KRas mutated pulmonary adenocarcinoma cells （Poster notice，General）
22.	2014/04/04	Inhibition of the growth factor midkine by a novel small molecule compound to treat pulmonary adenocarcinoma （Speech，General）
23.	2013/10/05	Inhibition of Midkine by a novel small molecule compound to treat non-small cell lung cancer （Speech，General）
24.	2013/06/19	THE USEFULNESS OF THE LEFT LATERAL DECUBITUS POSITION IN THE THORACOSCOPIC ESOPHAGECTOMY
25.	2013/04/08	Development of novel targeted therapies for non-small cell carcinoma by novel Midkine inhibitors （Poster notice，General）
26.	2012/09/21	Identification of novel Midkine inhibitors for the treatment of non-small cell lung cancer （Speech，General）
27.	2012/04/04	Targeting KRAS lung cancer in vivo by pulmonary surfactant-medicated gene transfer （Poster notice，General）
28.	2012/04/02	HSP90 inhibitor NVP-AUY922 exhibits the potent antiproliferative effect in gastrointestinal cancer cells with a lack of PTEN expression （Poster notice，General）
29.	2011/10/03	Anti-tumor effect in lung cancer by a combination treatment of novel HDAC inhibitors : SL142 or SL325 and retinoic acids （Speech，General）
30.	2011/04/04	Antitumor effect in human lung cancer by a combination treatment of novel histone deacetylase inhibitors: SL142 or SL325 and retinoic acids. （Poster notice）
31.	2011/04/04	Inhibition of mammalian target of rapamycin(mTOR)signaling by Temsirolimus as a potential therapeutic strategy for esophageal cancer treatment. （Poster notice）
32.	2010/09/23	Experimental approach to control peritoneal dissemination of colon cancer by targeting FAK. （Panelist at Symposium/Workshop (Other)）
33.	2010/09/22	Esophageal cancer exhibits a resistance to a novel IGF-1R inhibitor NVP-AEW541 with a maintained Ras-MAPK activity. （Poster notice，General）
34.	2010/04/20	The establishment of a new mouse model with orthotopic esophageal cancer showing the esophagostenosis
35.	2010/04/19	N-cadherin down-rgulation has antitumor effects in esophageal cancer
36.	2010/04/19	The anti-tumor effect of TAE226 , dual inhibitor of fak and IGF-IR , on non-small-cell lung cancer with EGFR mutain
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■ Belonging society

1.	1996～	Japan Surgical Society
2.	1997～	The Japanese Society of Gastroenterological Surgery
3.	2000～	American Association for Cancer Research
4.	2000～	Japanese Cancer Association
5.	2006～	Japan Gastroenterological Endoscopy Society