Faculty Information - Osamu Miyamoto

（Last updated : 2024-05-15 17:24:05）

Osamu Miyamoto
Department Kawasaki University of Medical Welfare ,

Position Professor with Special Assignment

■ Present specialized field

neurophysiology, neuropathology, general physiology, neuroscience (Key Word：neurophysiology, ischemic neuronal death, epilepsy, sponal cord injury, neurorehabilitation)

■ Journal

1.	2014/02/22	Neuroprotection of granulocyte colony-stimulating factor during the acute phase of transient forebrain ischemia in gerbils.
2.	2012/12	Calcium influx through the TRPV1 channel of endothelial cells (ECs) correlates with a stronger adhesion between monocytes and ECs
3.	2012/09	Quality evaluation of medical research by Kawasaki Medical School using bibliometric analysis.
4.	2009/01/11	Stage- and region-specific cyclooxygenase expression and effects of a selective COX-1 inhibitor in the mouse amygdala kindling model.
5.	2023/07/13	Age‑related brainstem degeneration through microRNA modulation in mice
6.	2022/03	A cerebrospinal fluid microRNA analysis: Progressive supranuclear palsy
7.	2021	The protective effect and mechanism of COA-Cl in acute phase afterspinal cord injury.
8.	2020/04/01	Light exercise without lactate elevation induces ischemic tolerance through the modulation of microRNA in the gerbil hippocampus.
9.	2019/07	Effects of intravesicular loading of a Ca 2+ chelator and depolymerization of actin fibers on neurotransmitter release in frog motor nerve terminals
10.	2019/07	Very Early Initiation Reduces Benefits of Poststroke Rehabilitation Despite Increased Corticospinal Projections.
11.	2019/06	Improvement of motor function induced by skeletal muscle contraction in spinal cord-injured rats
12.	2018/12	Role and limitations of rehabilitation-induced neural network remodeling after stroke.
13.	2018/07	Constraint-induced movement therapy improves efficacy of task-specific training after severe cortical stroke depending on the ipsilesional corticospinal projections.
14.	2017/11	Rehabilitative skilled forelimb training enhances axonal remodeling in the corticospinal pathway but not the brainstem-spinal pathways after photothrombotic stroke in the primary motor cortex.
15.	2017/02	Axonal remodeling in the corticospinal tract after stroke: how does rehabilitative training modulate it?
16.	2017/02	The Role of Endogenous Neurogenesis in Functional Recovery and Motor Map Reorganization Induced by Rehabilitative Therapy after Stroke in Rats.
17.	2016/12	Exercise in the early stage after stroke enhances hippocampal BDNF expression and memory function recovery
18.	2016/12	Neural network remodeling underlying motor map reorganization induced by rehabilitative training after ischemic stroke.
19.	2016/08/02	COA-Cl, a Novel Synthesized Nucleoside Analog, Exerts Neuroprotective Effects in the Acute Phase of Intracerebral Hemorrhage.
20.	2016/02	Ryanodine receptors contribute to the induction of ischemic tolerance.
21.	2014/05	Does methamphetamine affect bone metabolism?
22.	2014	c-Fos immunoreactivity of neural cells in intoxication due to high-dose methamphetamine.
23.	2013/04	Retinoic acid suppresses the adhesion and migration of human retinal pigment epithelial cells
24.	2013/02/14	Delayed administration of the nucleic acid analog 2Cl-C.OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke.
25.	2012/01/06	Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils.
26.	2011/05	Eicosapentaenoic Acid prevents memory impairment after ischemia by inhibiting inflammatory response and oxidative damage
27.	2011/01/03	Anti-oxidative effects of D-allose, a rare sugar, on ischemia-reperfusion damage following focal cerebral ischemia in rat.
28.	2008/09	Both amacrine and bipolar cells release glutamate in the rat retina after ischemia/reperfusion insult in vitro
29.	2008/08	3CB2, a marker of radial glia, expression after experimental intracerebral hemorrhage: role of thrombin.
30.	2008	Edaravone attenuates brain edema and neurologic deficits in a rat model of acute intracerebral hemorrhage
31.	2007	Expression and role of type I collagen in a rat spinal cord contusion injury model.
32.	2006	Delayed precursor cell marker response in hippocampus following cold injury-induced brain edema.
33.	2006	Neuroprotective effects of D-allose against retinal ischemia-reperfusion injury.
34.	2006	Unilateral ibotenic acid lesions of the prefrontal cortex reduce rotational behavior in 6-hydroxydopamine-lesioned rats
35.	2005	Co-expression of radial glial marker in macrophages/microglia in rat spinal cord contusion injury model
36.	2005	Different expression of macrophages and microglia in rat spinal cord contusion injury model at morphological and regional levels
37.	2005	Stage and region dependent expression of a radial glial marker in commissural fibers in kindled mice
38.	2005	Vascular changes in the rat brain during chronic hypoxia in the presence and absence of hypercapnia
39.	2004	Delayed precursor cell markers expression in hippocampus following cold-induced cortical injury in mice.
40.	2004	Localization of nestin in amygdaloid kindled rat: an immunoelectron microscopic study
41.	2004	Post-traumatic moderate systemic hypothermia reduces TUNEL positive cells following spinal cord injury in rat
42.	2004	Regional expression of the radial glial marker vimentin at different stages of the kindling process
43.	2004	The Ginkgo biloba extract (EGb 761) provides a neuroprotective effect on retinal ganglion cells in a rat model of chronic glaucoma
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■ Presentation

1.	2013/03/29	The involvement of ryanodine receptors on ischemic preconditioning （Poster notice，General）
2.	2013/03/28	Delayed administration of the nucleic acid analog 2Cl-C.OXT-A attenuates brain damage and enhances functional recovery after ischemic stroke （Poster notice，General）
3.	2013/03/27	The effects of increase of BDNF in hippocampus on recovery of cognitive function in cerebral infarction model rats （Poster notice，General）
4.	2012/09/18	The effects of exercise in acute-phase after cerebral infarction on the recovery of cognitive and motor dysfunction in cerebral infarction model rats （Poster notice，General）
5.	2009/08/01	Stage- and region-specific cyclooxygenase expression and effects of a selective COX-1 inhibitor in the mouse amygdala kindling model. （Poster notice，General）
6.	2009/08/01	Delayed protease inhibitor treatment reduces brain damage after intracerebral hemorrhage in rat （Poster notice，General）
7.	2021/07/31	The novel nucleic acid analog, COA-Cl exerted the neuroprotective effect in acute phase after spinal cord injury （Poster notice，General）
8.	2021/03/30	The characteristics of Ca2+ release via ryanodine receptors are altered in the hippocampus of depression-like model mice. （Poster notice，General）
9.	2020/07/30	Motor and memory functions of cerebral hypoperfusion model rats by microsphere embolism. （Poster notice，General）
10.	2020/03/18	The protective effect and mechanism of COA-Cl in acute phase after spinal cord injury （Speech，General）
11.	2020/03/17	Alteration of Ca2+ release via ryanodine receptors in the hippocampus of depression-like model mice. （Abstract Only，General）
12.	2019/09/26	Improvement of motor function induced by skeletal muscle contraction in spinal cord injury rats （Poster notice，General）
13.	2019/09/18	The effects of treadmill exercise in acute stage after stroke on memory function in a novel rat model of vascular dementia （Poster notice，General）
14.	2019/07/26	Characteristics and functions of cerebral hypoperfusion model rats by microsphere embolism. （Poster notice，General）
15.	2019/07/26	Medical Education Partnership with Kawasaki Senior High School Attached to Kawasaki Medical School （Speech，General）
16.	2019/03/30	Improvement of motor function induced by skeletal muscle contraction in spinal cord injury rats （Poster notice，General）
17.	2019/03/29	Characteristics of motor and memory functions in cerebral hypoperfusion model rat by microspheres （Poster notice，General）
18.	2018/11/16	The involvement of ryanodine receptors to the effect of ECS on the behavioral changes in mouse depression model. （Poster notice，General）
19.	2018/11/05	Time and use dependent effects of constraint induced movement therapy (CIMT) on functional recovery and neural network remodeling after severe stroke in rats （Poster notice，General）
20.	2018/11/04	The effects of embolism induced by varied particle number of microsphere on motor and cognitive functions and parkinsonism. （Poster notice，General）
21.	2018/07/27	Constraint-induced movement therapy improves efficacy of task-specific training after severe cortical stroke depending on the ipsilesional corticospinal projections （Poster notice，General）
22.	2018/07/27	Constraint-induced movement therapy improves efficacy of task-specific training after severe cortical stroke depending on the ipsilesional corticospinal projections （Poster notice，General）
23.	2018/03/30	The involvement of ryanodine receptors in depression-like model mouse. （Poster notice，General）
24.	2018/03/29	Improvement of motor function by electrical muscle stimulation after spinal cord injury in rats. （Poster notice，General）
25.	2018/03/28	Neural network remodeling induced by rehabilitatitive training after stroke: Effectiveness and limitation （Speech，Panelist at Symposium/Workshop (Appointed)）
26.	2018/03/28	The novel rat model of vascular dementia by microsphere embolism （Poster notice，General）
27.	2017/07/20	Changes in descending spinal tract after post-stroke rehabilitation （Poster notice，General）
28.	2017/03/30	Neural network remodeling induced by task-specific rehabilitative training after stroke （Speech，Panelist at Symposium/Workshop (Appointed)）
29.	2017/03/30	The effect of ECT on Ca²⁺ signaling pathway in mouse depression model-involvement of ryanodine receptors. （Poster notice，General）
30.	2016/11/14	Customary exercise prevents the poststroke memory dysfunction by constitutive elevation of hippocampal BDNF （Poster notice，General）
31.	2016/09/25	The preventive effects of exercise on poststroke memory dysfunction （Poster notice，General）
32.	2016/07/22	The customary exercise prevents the poststroke memory dysfunction by elevation of hippocampal BDNF （Poster notice，General）
33.	2016/07/21	Axonal remodeling underlying motor map reorganization induced by rehabilitative therapy after stroke （Poster notice，General）
34.	2016/03/24	Neural network remodeling underlying motor map reorganization induced by reh abilitative therapy after stroke （Poster notice，General）
35.	2016/03/24	The mechanism of motor map reorganization induced by rehabilitative therapy after stroke （Speech，Panelist at Symposium/Workshop (Applied)）
36.	2016/03/23	The potential neuroprotective effects of COA-Cl against stroke events （Speech，Panelist at Symposium/Workshop (Applied)）
37.	2015/07/28	Neural network reorganization induced by rehabilitation therapy after stroke （Poster notice，General）
38.	2015/07/18	The exercise in early stage poststroke reduces neuronal apoptosis in hippocampus by elevation of BDNF （Poster notice，General）
39.	2015/06/28	The early elevation of hippocampal BDNF by exercise after cerebral microemboli reduces the apoptosis of neuron （Poster notice，General）
40.	2015/03/23	Spatiotemporal analysis of motor map reorganization after stroke （Poster notice，General）
41.	2015/03/23	The early elevation of hippocampal BDNF by exercise after stroke protects ne urodegeneration （Poster notice，General）
42.	2013/11/09	The exercise at early stage after stroke enhanced the recovery of memory function via BDNF elevation in the hippocampus in stroke model rats. （Poster notice，General）
43.	2013/07/26	A new web-based lecture evaluation system at Kawasaki Medical School （Poster notice，General）
44.	2011/11/14	A STUDY ON THE POSSIBLE ROLE OF SYNAPTIC VESICLES AS A Ca2+ STORE FOR Ca2+-INDUCED Ca2+ RELEASE IN FROG MOTOR NERVE TERMINALS. （Poster notice，General）
45.	2010/05/20	Morphological changes of NG2 cell in kindled mouse （Speech，General）
46.	2010/05/20	Possible roles of synaptic vesicles in use-dependent amplification of transmitter exocytosis via RyRs in frog motor nerve terminals （Speech，Panelist at Symposium/Workshop (Other)）
47.	2008/03/25	Activation of microglia in the kindling model （Speech，General）
48.	2008/03/25	Effect of free radical scavenger on oxidative DNA damage after experimental intracerebral hemorrhage （Poster notice，General）
49.	2007/05/20	Effect of Edaravone on brain edema and neurological deficits after experimental intracerebral hemorrhage
50.	2007/03/20	NG2 positive cells and its lineage between other glial cells in rat spinal cord injury model （General）
51.	2007/03/20	Radial glial marker expression after experimental intracerebral hemorrhage （General）
52.	2006/03/30	Effect of rare sugar, D-allose on rat retinal ischemic model （General）
53.	2006/03/30	Stage and region dependent expression of a radial glial marker in commissural fibers in kindled mice （General）
54.	2006/03/30	The involvement of cyclooxygenase in seizure development in kindling mice （General）
55.	2005/05/18	Expression and role of macrophages and microglia in rat spinal cord injury （General）
56.	2005/05/18	The protective effects of D-allose on ischemic brain （General）
57.	2004/07/31	Vascular changes in the rat brain by chronic hypoxia with and without Hypercapnia
58.	2004/06/02	Mechanisms of the anti-ischenmic effect of vagus nerve stimulation in the gerbil hippocampus （General）
59.	2004/06/02	Spatio/temporal regeneration of oligodendrocyte progenitor cell after spinal cord injury in adult rodents （General）
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■ Belonging society

1.	1989/04～	the Physiological Society of Japan
2.	1993/04～	the Japanese Society Physical Fitness and Sports Medicine
3.	1994/04～	the Japan Neuroscience Society
4.	1997/04～	the Japanese Society of Cerebral Blood Flow and Metabolism
5.	2016/04～	Japanese Journal of Neuropsychopharmacology
6.	2017/02～	Japanese Society for Neural Repair and Neurorehabilitation
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