Faculty Information - Koichiro Shimoya

Current specialization

Publications

Journal Articles

Presentations

（Last updated : 2025-07-02 15:11:54）

Koichiro Shimoya
Department Kawasaki Medical School Kawasaki Medical School, Department of Obstetrics and Gynecology 1,

Position Professor with Special Assignment

■ Current specialization

Obstetrics and gynecology (Key Word：maternal fetal medicine, reproductive immunology, fertility and steriliry)

■ Publications

1.	2022/08	Intrapartum Hypoxia, Cerebral Palsy
2.	2015/07	Relationship between plasma oxidative stress level, oxidative stress-related gene polymorphisms and dietary habits.「DNA Polymorphism」
3.	2012/05	Relationship between Uncoupling protein 1 polymorphisms and daily lifestyle「DNA polymorphism」

■ Journal Articles

1.	2023/07/24	Protease-Activated Receptor 1 (PAR1) Expression Contributes to HPV-Associated Oropharyngeal Cancer Prognosis.
2.	2023/01	A nationwide study of obstetric management and outcomes in premature rupture of membrane at term: Report from the Perinatology Committee, Japan Society of Obstetrics and Gynecology, 2017-2018
3.	2023/01	Guidelines for obstetrical practice in Japan: Japan Society of Obstetrics and Gynecology and Japan Association of Obstetricians and Gynecologists 2020 edition.
4.	2022/08/17	Impact of surgical adhesion barrier on significant adhesion during a repeat cesarean section
5.	2022/07	Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines.
6.	2021/04/11	A case of total hysterectomy due to massive maternal bleeding immediately after fetoscopic laser surgery for twin-twin transfusion syndrome
7.	2020/11	Co-implantation of Tumor and Extensive Surrounding Tissue Improved the Establishment Rate of Surgical Specimens of Human-Patient Cancer in Nude Mice:Toward the　Goal of Universal Individualized Cancer Therapy
8.	2020/05	Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model.
9.	2019/10/18	A case of intrauterine fetal death after thrombocytopenia in a patient with systemic lupus erythematosus and antiphospholipid syndrome
10.	2019/06	Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model.
11.	2017/10	Vasohibin-1 Is a Poor Prognostic Factor of Ovarian Carcinoma.
12.	2017/02	Maternal Depression and Mother-to-Infant Bonding: The Association of Delivery Mode, General Health and Stress Markers
13.	2016/07	Significance of histologic pattern of carcinoma and sarcoma components on survival outcomes of uterine carcinosarcoma.
14.	2016/06	Guillain-Barre syndrome after trivalent influenza vaccination during pregnancy.
15.	2015/09	Effect of vitamin K2 on the development of stress-induced osteopenia in a growing senescence-accelerated mouse prone 6 strain
16.	2015/04	Massive cystic degeneration of a uterine leiomyoma in a patient with autosomal dominant polycystic kidney disease.
17.	2014/12	Association Between Sexual Health and Delivery Mode
18.	2014/11	Abnormal pressure-wave reflection in pregnant women with chronic hypertension: association with maternal and fetal outcomes.
19.	2014/07	Timing of cisplatin administration for chemoradiotherapy in transgenic mice bearing lens tumors.
20.	2012/10	Successful management of chemotherapy in a stage IV ovarian cancer patient with chronic renal failure
21.	2012/02	A case of serous endometrial intraepithelial carcinoma with p53 positivity for six years.
22.	2011/12	A case of extremely rare ovarian tumor: Primary ovarian adenomyoma
23.	2011/08	Change of salivary stress marker concentrations during pregnancy: Maternal depressive status suppress changes of those levels.
24.	2011	Effects of 4-hydroxy-2-nonenal, a major lipid peroxidation-derived aldehyde, and N-acetylcysteine on the cyclooxygenase-2 expression in human uterine myometrium.
25.	2010/10	The effect of tumor-associated protein RCAS1 gene silencing on blood pressure and urinary protein excretion in pregnant mouse: a pilot study.
26.	2010/09	Maternal blood serum and plasma human tumor-associated antigen RCAS1 during the course of uncomplicated pregnancies: a prospective study.
27.	2010/05	Human C-reactive protein enhances vulnerability of immature rats to hypoxic-ischemic brain damage: a preliminary study.
28.	2010/03	Oxidative stress-induced S100B protein from placenta and amnion affects soluble Endoglin release from endothelial cells.
29.	2010/03	Oxidative stress-induced S100B protein from placenta and amnion affects soluble Endoglin release from endothelial cells.
30.	2010/02	Temporal and spatial expression of tumor-associated antigen RCAS1 in pregnant mouse uterus.
31.	2010/02	Temporal and Spatial Expression of Tumor-Associated Antigen RCAS1 in Pregnant Mouse Uterus.
32.	2009/11	Use of uterine fundal pressure maneuver at vaginal delivery and risk of severe perineal laceration.
33.	2009/09	Elective cesarean delivery at 38 weeks' gestation: is the timing too early?
34.	2008/02	Maternal urinoma during pregnancy.
35.	2008/01	Is 38 weeks late enough for elective cesarean delivery?
36.	2008/01	The human tumor-associated antigen RCAS1 in pregnancies complicated by pre-eclampsia.
37.	2008	Combination chemotherapy of intraperitoneal carboplatin and intravenous paclitaxel in suboptimally debulked epithelial ovarian cancer.
38.	2007/12	Endoscopic third ventriculostomy during pregnancy.
39.	2007/11	Relationship between human tumor-associated antigen RCAS1 and gestational diabetes mellitus.
40.	2007/06	Maternal positioning and fetal positioning in utero.
41.	2007/06	Sonographic femur length to trunk cross area ratio: prediction of fetal outcome in 30 cases in which micromelia was suspected.
42.	2007	Level of S100B protein expression in the amnion at various gestational ages in the third trimester of normal pregnancies.
43.	2007	Pregnancy and delivery with Kindler syndrome.
44.	2006/12	S100B protein expression in the amnion and amniotic fluid in pregnancies complicated by pre-eclampsia.
45.	2006/11	Post-ischemic hypothermia reduced IL-18 expression and suppressed microglial activation in the immature brain.
46.	2006/10	Transient local overexpression of human vascular endothelial growth factor (VEGF) in mouse feto-maternal interface during mid-term pregnancy lowers systemic maternal blood pressure.
47.	2006/09	A decrease of cell proliferation by hypothermia in the hippocampus of the neonatal rat.
48.	2006/09	Mid-second trimester measurement of fetal nasal bone length in the Japanese population.
49.	2006/09	Spontaneous rupture of uterine surface varicose veins in pregnancy: a case report.
50.	2006/08	Prospective study of non-closure or closure of the peritoneum at cesarean delivery in 124 women: Impact of prior peritoneal closure at primary cesarean on the interval time between first cesarean section and the next pregnancy and significant adhesion at second cesarean.
51.	2006/08	Rapid detection of trisomy 21 by gene dosage analysis using quantitative real-time polymerase chain reaction.
52.	2006/08	Reduction of aquaporin-8 on fetal membranes under oligohydramnios in mice lacking prostaglandin F2 alpha receptor.
53.	2006/06	Cesarean delivery after successful external cephalic version of breech presentation at term.
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■ Presentations

1.	2016/11/22	Trial development of Maternal and Child Health Handbook standard format using HL7 CDA （Speech，General）
2.	2015/11/04	Expanded electronic Maternal and Child Health Handbook -Provision of medical information by SS-MIX- （Speech，General）
3.	2015/11/03	Analysis of Maternal and Child Health Handbook using ICF （Poster notice，General）
4.	2013/11/21	Relationship between oxidative stress level, oxidative stress-related gene polymorphisms and daily lifestyle. （Poster notice，General）
5.	2012/11/08	Relationship between Stress-related gene polymorphisms and appropriate assistance in the workplace （Poster notice，General）
6.	2012/09/18	The maternal-to-fetal kinetic analysis of Fractalkine/CX3CL1 （General）
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