Faculty Information - Yano Hiromi

（Last updated : 2026-03-05 14:58:26）

Yano Hiromi
Department Kawasaki University of Medical Welfare ,

Position Professor

■ Journal

1.	2026/03/04	Prebiotic diet enhances suppression of tumor necrosis factor–alpha production in response to lipopolysaccharide after exhaustive exercise
2.	2026/02/27	Influence of dietary fiber fermentability on DSS-induced colitis severity and muscle wasting via gut microbiota
3.	2025/10/28	Partially hydrolyzed guar gum intake alleviates lipopolysaccharide-induced systemic inflammation via gut microbial alteration in mice
4.	2025/08/14	Physical activity is associated with reduced mild depression and altered gut microbiota in Japanese adult women
5.	2024/12/19	Nopalea cochenillifera regulates the immune response and gut microbiota in mice.
6.	2024/09/26	Dietary intervention outperforms fecal microbiota transplantation from exercised and/or lean donors in improving metabolic phenotypes of western diet-fed obese mice
7.	2024/09/06	Frequent icing stimulates skeletal muscle regeneration following injury with necrosis in a small fraction of myofibers in rats
8.	2024/03/01	Wet-type grinder-treated okara modulates gut microbiota composition and attenuates obesity in high-fat-fed mice
9.	2024/02/01	Relationship between gut microbial community and short-chain fatty acid production in Tlr5 knockout mice after voluntary exercise
10.	2023/10/13	Anti-inflammatory properties of skeletal muscle protects against muscle wasting in colitis of dextran sulfate sodium model mice
11.	2023/09/04	Antidepressant properties of voluntary exercise mediated by gut microbiota
12.	2023/04/26	Aerobic exercise training-induced alteration of gut microbiota composition affects endurance capacity
13.	2023/04/01	Icing after skeletal muscle injury with necrosis in a small fraction of myofibers limits iNOS-expressing macrophage invasion and facilitates muscle regeneration
14.	2022/08/09	Acetyl-L-carnitine attenuates Poly I:C-induced sickness behavior in mice
15.	2022/06/02	LPS-induced TNF-α production is attenuated by intake with PHGG via gut microbial fermentation in mice
16.	2021/04/20	Effect of partially hydrolyzed guar-gum treatment on fecal pH in mice fed with a high-fat-diet
17.	2020/09/17	Effects of voluntary exercise on plasma and urinary metabolites and gut microbiota in mice fed with a high-fat-diet
18.	2020/08/19	The effect of voluntary exercise on gut microbiota in partially hydrolyzed guar-gum intake mice under high-fat-diet feeding.
19.	2020/06	Improved physicochemical and functional properties of okara, a soybean residue, by nanocellulose technologies for food development – A review
20.	2020/02	Dietary cellulose nanofiber modulates obesity and gut microbiota in high-fat-fed mice.
21.	2020/01	Effect of dietary cellulose nanofiber and exercise on obesity and gut microbiota in mice fed a high-fat-diet
22.	2019/10	Gene expression profiles for macrophage in tissues in response to different exercise training protocols in senescence mice
23.	2019/09	Content Analysis of In-school Training Regarding the Food Allergy Response Manuals Issued by Prefectures
24.	2019/09	Sparassis crisps intake improves the reduced lipopolysaccharide-induced TNF-α production that occurs upon exhaustive exercise in mice.
25.	2018/10	Special issue "Exercise and inflammation" Reduction of real-time imaging of M1 macrophage chemotaxis toward damaged muscle cells is PI3K-dependent
26.	2018/05	Benefits of post-stress immunosuppression: a viewpoint from exercise immunology
27.	2018/05	Reduction of voluntary physical activity in mice induced by toll-like receptor 7 agonist R-848.
28.	2018/02	Resistance training prevents muscle fibrosis and atrophy via down-regulation of C1q-induced Wnt signaling in senescent mice.
29.	2018/01	Altered gut microbiota by voluntary exercise induces a high physical activity in high-fat diet mice.
30.	2015/05	Palmitoleic acid induces the cardiac mitochondrial membrane permeability transition despite the presence of L-carnitine
31.	2014/01	Exhaustive exercise increases the TNF-a production in response to flagellin via the upregulation of toll-like receptor 5 in the large intestine in mice.
32.	2013/11	Curcumin attenuates oxidative stress following downhill running-induced muscle damage.
33.	2013/11	Mechanisms of chronic inflammation improvement by exercise: Focus on immune response of local tissue
34.	2013/10	Exercise training attenuates adipose tissue fibrosis in diet-induced obese mice.
35.	2013/09	Exercise attenuates M1 macrophages and CD8+ T cells in adipose tissue of obese mice.
36.	2013/07	Relationship between macrophage differentiation and the chemotactic activity toward damaged myoblast cells
37.	2012/11	The suppression of tumor necrosis factor-alpha production in response to pathogen stimulation by strenuous exercise and underlying mechanisms
38.	2012/08	Exercise training attenuates hepatic inflammation, fibrosis and macrophage infiltration during diet induced-obesity in mice.
39.	2012/01	Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice.
40.	2011/09	Protective action of L-carnitine on cardiac mitochondrial function and structure against fatty acid stress.
41.	2011/01	Impact of omega-5 gliadin on wheat-dependent exercise-induced anaphylaxis in mice
42.	2010/11	Exhaustive exercise reduces TNF-a and IFN-a production in response to R-848 via toll-like receptor 7 in mice
43.	2010/10	Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice
44.	2010/09	L-carnitine is essential to beta-oxidation of quarried fatty acid from mitochondrial membrane by PLA(2)
45.	2010/05	Exhaustive exercise reduces tumor necrosis factor-alpha production in response to lipopolysaccharide in mice
46.	2009	Lipopolysaccharide-induced tumor necrosis factor (TNF)-a production depends on exercise intensity in rats.
47.	2009	Voluntary physical activity increases the immune responses of Kupffer cells in rats.
48.	2008	Flow cytometric analysis of Ca2+-induced membrane permeability transition of isolated rat river mitochondria.
49.	2008	High-dose of lipopolysaccharide pre-treatment prevents OVA-induced anaphylactic decreases in rectal temperature in the immunized mice.
50.	2008	L-Carnitine suppresses oleic acid-induced membrane permeability transition of mitochondria.
51.	2008	Lipopolysaccharide-induced monocyte chemotactic protein-1 is enhanced by suppression of nitric oxide production and it depends on poor CD14 expression on surface in skeletal muscle.
52.	2008	Mechanism of 3-nitropropionic acid-induced membrane permeability transition of isolated mitochondria and its suppression by L-carnitine.
53.	2008	Salmonella administration induces a reduction of wheel-running activity via a TLR5-, but not a TLR4-, dependent pathway in mice.
54.	2008	The reduction of voluntary physical activity after Poly I:C injection is independent of the effect of Poly I:C-induced interferon-beta in mice.
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■ Presentation

1.	2025/07/04	Effect of dietary fiber intake on motivation for physical activity. （ポスター掲示，一般）
2.	2025/07/04	The gut microbiota in college athletes insduces spontaneous activity of its fecal transplanted mice. （ポスター掲示，一般）
3.	2025/07/03	Negative effect of FMT from exercised mice on SDS induced depression-like behavior. （ポスター掲示，一般）
4.	2025/07/02	Gut microbiota enhances suppression of innate immune response after exhaustive exercise. （口頭，一般）
5.	2025/07/02	Predicting of drowning by using both VR video viewing before swimming exposure and heart rate monitoring system during long-distance swimming. （ポスター掲示，一般）
6.	2024/09/10	FMT from voluntary exercised mice as an ineffectiveness for attenuation of depression-like behavior （ポスター掲示，一般）
7.	2024/09/10	Immune regulations as the respective survival strategies between host and gut microbiota 　-A view point of the exercise immunology- （ポスター掲示，一般）
8.	2024/09/10	Influence of physical activity on gut microbiota in adult women with mild depression （ポスター掲示，一般）
9.	2024/09/10	Partially Hydrolyzed Guar Gum Intake Contributes to the Suppression of LPS-induced Systemic Inflammation via an Increase in the Regulatory T Cells in Intestinal Lamina Propria of Mice （ポスター掲示，一般）
10.	2024/09/02	Effectiveness of post-injury icing on skeletal muscle regeneration depends on the magnitude of muscle damage （口頭，シンポジウム・ワークショップパネル（指名））
11.	2023/07/06	Benefical effects of post-injury icing on skeletal muscle regeneration in a new injury model with necrosis limited to a small fraction of myofibers in rat. （ポスター掲示，一般）
12.	2023/07/06	Relationship between gut microbiota community and short-chain fatty acid production in Tlr5 knockout mice after voluntary exercise. （ポスター掲示，一般）
13.	2023/07/05	Effect of voluntary exercise on depression in high-fat-fed mice. （ポスター掲示，一般）
14.	2023/07/05	Preventive effect of exercise on depression-like behavior via decreasing hippocampal TSPO. （ポスター掲示，一般）
15.	2022/10/27	Gut microbiota and short-chain fatty acids in TLR5 gene-deficient mice （口頭，一般）
16.	2022/10/25	Additive benefits of exercise and dietary inulin supplementation on physical characteristics and glucose metabolism （ポスター掲示，一般）
17.	2022/10/25	Effect of partially hydrolyzed guar-gum intake on LPS-induced systemic inflammation via gut microbial fermentation in mice （ポスター掲示，一般）
18.	2022/10/25	Exercise alters gut microbiota and induces prevention of depression-like behavior in mice （ポスター掲示，一般）
19.	2022/10/25	Noradrenergic stimulation increases T cell-induced acetylcholine production （ポスター掲示，一般）
20.	2022/10/25	Protective effect of acute and chronic acetyl-L-carnitine administration on Poly I:C-induced fatigue-like behavior in mice （ポスター掲示，一般）
21.	2022/10/25	The combined effect of PHGG and exercise on obesity via changes in gut microbiota （ポスター掲示，一般）
22.	2021/09/17	The effects of voluntary exercise combined with PHGG intake on the relationship between gut microbiota and host parameters. （口頭，一般）
23.	2020/12/01	Impact of dietary cellulose nanofibrils on obesity and gut microbiota in high-fat diet-fed mice （口頭，一般）
24.	2020/02/13	The complementary effect of PHGG intake and voluntary exercise on the gut microbiota in high-fat-diet induced obese mice （口頭，一般）
25.	2019/11/09	Impact of wheel running on behavioral anxiety and gut microbiota in mice fed with a high-fat-diet （ポスター掲示，一般）
26.	2019/11/09	Regulation of gut microbiota-induced metabolites by voluntary exercise in a high-fat-diet fed mice （ポスター掲示，一般）
27.	2019/11/09	The complementary effect of dietary-fiber intake and voluntary exercise on the gut microbiota in high-fat-diet induced obese mice （ポスター掲示，一般）
28.	2019/11/08	Relationship between physical activity and gut microbiota in exercised TLR5 deficient mice （口頭，一般）
29.	2019/07/06	Changes in the gut microbiota of highly trained distance runners during a summer training camp in a hot environment. （ポスター掲示，一般）
30.	2019/07/05	Effects of voluntary exercise on plasma and urinary metabolites and gut microbiota in a high-fat-diet fed mice. （口頭，一般）
31.	2019/07/05	Effects of wheel running on blood-brain-barrier permeability in high-fat-diet fed mice. （口頭，一般）
32.	2019/07/05	Voluntary wheel running accelerates PHGG-induced gut environmental improvement in high-fat-diet fed mice. （口頭，一般）
33.	2019/07/05	Voluntary wheel running influences on dynamics of gut microbiota F/B ratio in TLR5 deficient mice. （口頭，一般）
34.	2018/10/04	Management of physical education classes during students' menstruation period （ポスター掲示，一般）
35.	2018/09/19	Effect of water temperature on the regional pulse wave velocity during water immersion （口頭，一般）
36.	2018/09/08	The influence of gut microbiota on Tnf-alpha expression in skeletal muscle of antibiotic treated mice （口頭，一般）
37.	2018/07/07	The preventive effect of voluntary physical exercise on mental disorders in high-fat-diet-mice. （口頭，一般）
38.	2018/07/06	Gut microflora diversity is induced by resistance training in aged mice, but its acquired diversity might not be contributed with the high physical performance. （口頭，一般）
39.	2018/07/06	The different responses in regional pulse wave velocity to water immersion at 30^oC. （ポスター掲示，一般）
40.	2018/07/05	Exploring beneficial impact of physical activity from body compositions of fecal occult blood-positive patients with colon polyps in Japan. （口頭，一般）
41.	2017/10/27	Aerobic and resistance training-induced attenuation of chronic inflammation involves functional change of macrophages in various tissues of senescent mice. （ポスター掲示，一般）
42.	2017/10/27	Reduced serum C1q by resistance training is related to the prevention of sarcopenia. （ポスター掲示，一般）
43.	2017/07/27	A dear partner of heart mitochondria is L-carnitine. （口頭，特別講演・招待講演など）
44.	2017/07/14	Chronic responses of inflammation and macrphpage function to exercise training in various tissues of senescence mice. （口頭，一般）
45.	2017/07/13	Altered gut microbiota by voluntary exercise in donor mice may contribute to high physical activity in recipient mice. （ポスター掲示，一般）
46.	2017/07/13	Gut microbiota in exercise trained Toll-like receptor 5 deficient mice inhibits fatty liver and hepatic inflammation. （ポスター掲示，一般）
47.	2017/07/12	Relationship between the stability and emotional stability of sports performance and changes in gut microbiota with mental and physical stress. （ポスター掲示，一般）
48.	2016/06/03	Voluntary exercise attenuates obesity and systemic inflammation by alteration of gut microbiota in TLR5-deficient mice. （ポスター掲示，一般）
49.	2016/06/01	The gut microbiota of TLR5-deficient mice display elevated voluntary physical activity. （ポスター掲示，一般）
50.	2015/11/06	The adventures of macrophages toward the damaged skeletal muscle （口頭，特別講演・招待講演など）
51.	2015/07/08	Flagellin receptor TLR5-deficient mice display elevated voluntary physical activity associated with changes in gut microbiota. （ポスター掲示，一般）
52.	2015/07/08	Tumor necrosis factor-alpha production in response to pathogen stimulation via TLRs by strenuous exercise and underlying mechanisms. （ポスター掲示，一般）
53.	2015/07/07	Voluntary physical exercise affects metabolic syndrome by alteration of gut microbiota in TLR5-deficient mice. （ポスター掲示，一般）
54.	2014/05/30	Flagellin-induced TNF-alpha production is enhanced by exhaustive exercise-induced catecholamine via beta-adrengic receptor. （口頭，シンポジウム・ワークショップパネル（指名））
55.	2014/05/29	Real-time imaging of macrophage chemotaxis toward damaged muscle cells is PI3K-dependent. （ポスター掲示，シンポジウム・ワークショップパネル（指名））
56.	2014/05/28	L-Carnitine induces protection of mitochondria, and that might contribute to inhibit fatty acid-induced arrhythmias of heart. （ポスター掲示，一般）
57.	2013/09/09	Relationship between macrophage differentiation and the chemotactic activity toward damaged muscle cells. （ポスター掲示，一般）
58.	2013/09/09	The effect of voluntary exercise training on LPS-induced TNF-alpha concentration after exhaustive exercise. （ポスター掲示，一般）
59.	2012/10/31	Protective action of L-carnitine on cardiac mitochondrial function and structure （口頭，一般）
60.	2011/07	Curcumin attenuates oxidative stress via suppression of MCP-1 production following downhill running induced muscle damage. （ポスター掲示，一般）
61.	2011/07	Moderate exercise training do not improve LPS-induced TNF-alpha reduction after exhaustive exercise. （ポスター掲示，一般）
62.	2010/05	The response of voluntary physical activity to R-848 via TLR7 in mice. （ポスター掲示，一般）
63.	2010/05	TNF-alpha production in response to LPS is inhibited by exercise training in rats. （ポスター掲示，一般）
64.	2009/09	Exhaustive exercise reduces TNF-alpha and IFN-gamma production in response to R-848 via toll-like receptor 7 in mice. （口頭，一般）
65.	2009/05/27	The response of voluntary physical activity via TLR3 and TLR7/8 in mice. （口頭，一般）
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■ Lecturer and lecture

2015/11

Wonders of the innate immune systems for host defense after intense exercise. (Dondaegu, Korea)

■ Belonging society

1.	2001～	The International Society of Exercise and Immunology
2.	2002～	Japanese Society of Exercise and Immunology