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1.
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2019/08
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Binimetinib, a novel MEK1/2 inhibitor, exerts anti-leukemic effects under inactive status of PI3Kinase/Akt pathway.
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2.
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2019/03
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Mice with Calr mutations homologous to human CALR mutations only exhibit mild thrombocytosis.
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3.
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2018/03
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Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents.
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4.
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2018/01
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Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma.
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5.
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2017/09
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A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study).
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6.
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2017/05
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Calreticulin mutant mice develop essential thrombocythemia that is ameliorated by the JAK inhibitor ruxolitinib.
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7.
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2017/05
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Effects of mogamulizumab in adult T-cell leukemia/lymphoma in clinical practice.
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8.
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2017/03
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TET2 mutation in diffuse large B-cell lymphoma.
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9.
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2017/03
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Development of a complete human IgG monoclonal antibody to transferrin receptor 1 targeted for adult T-cell leukemia/lymphoma.
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10.
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2017/03
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Differences in Hematological and Clinical Features Between Essential Thrombocythemia Cases With JAK2- or CALR-Mutations.
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11.
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2016/05
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Aberrant PD-L1 expression through 3'-UTR disruption in multiple cancers.
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12.
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2016/05
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All-trans retinoic acid and interferon-alpha increase CD38 expression on adult T-cell leukemia cells and sensitize them to T cells bearing anti-CD38 chimeric antigen receptors.
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13.
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2016/04
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Splenic irradiation provides transient palliation for symptomatic splenomegaly associated with primary myelofibrosis: a report on 14 patients.
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14.
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2016/02
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Variegated RHOA mutations in adult T-cell leukemia/lymphoma.
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15.
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2015/12
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Surrounding Gastric Mucosa Findings Facilitate Diagnosis of Gastric Neoplasm as Gastric Adenoma or Early Gastric Cancer.
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16.
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2015/12
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TET2 Mutation in Adult T-Cell Leukemia/Lymphoma.
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17.
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2015/11
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Nasopharyngeal carcinoma with bone marrow metastasis: positive response to weekly paclitaxel chemotherapy.
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18.
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2015/11
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Integrated molecular analysis of adult T cell leukemia/lymphoma.
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19.
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2015/09
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Analysis of the molecular mechanism underlying bone marrow necrosis with acute lymphoblastic leukemia.
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20.
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2015/04
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Gene expression profiling of loss of TET2 and/or JAK2V617F mutant hematopoietic stem cells from mouse models of myeloproliferative neoplasms.
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21.
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2015/01
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Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator.
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22.
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2014/12
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Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase.
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23.
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2014/04
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Clinical outcomes of AIDS-related Burkitt lymphoma: a multi-institution retrospective survey in Japan.
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24.
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2013/01
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Effect of L-thyroxine replacement on apolipoprotein B-48 in overt and subclinical hypothyroid patients.
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25.
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2012/10
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TET2 is essential for survival and hematopoietic stem cell homeostasis.
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26.
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2012/09
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Acute myeloid leukemia in clinical practice: a retrospective population-based cohort study in Miyazaki Prefecture, Japan.
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27.
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2012/08
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Linezolid-induced pure red cell aplasia in a patient with Staphylococcus epidermidis infection after allogeneic stem cell transplantation.
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28.
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2012/06
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T-cell immunotherapy with a chimeric receptor against CD38 is effective in eradicating chemotherapy-resistant B-cell lymphoma cells overexpressing survivin induced by BMI-1.
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29.
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2012/03
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The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo.
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30.
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2012/02
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T-cell immunotherapy with a chimeric receptor against CD38 is effective in eliminating myeloma cells.
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31.
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2011/11
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S-1 induced secondary acute erythroid leukemia with a chromosome inv(12)(p13;q13).
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32.
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2011/10
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Medical cost analysis for antifungal prophylaxis in neutropenic patients with hematological malignancies: a systematic simulation analysis.
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33.
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2011/06
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Expression of CD38 with intracellular enzymatic activity: a possible explanation for the insulin release induced by intracellular cADPR.
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34.
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2010/12
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The immature platelet fraction is a useful marker for predicting the timing of platelet recovery in patients with cancer after chemotherapy and hematopoietic stem cell transplantation.
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35.
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2010/10
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Synergistic and persistent effect of T-cell immunotherapy with anti-CD19 or anti-CD38 chimeric receptor in conjunction with rituximab on B-cell non-Hodgkin lymphoma.
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36.
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2010/09
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Micafungin does not influence the concentration of tacrolimus in patients after allogeneic hematopoietic stem cell transplantation.
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37.
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2010/06
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Immature platelet fraction measurement in patients with chronic liver disease: a convenient marker for evaluating cirrhotic change.
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38.
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2010/03
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Automated assay for determining cellular cholesterol using a random access chemistry analyser.
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39.
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2010/02
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Lineage switch from precursor B cell acute lymphoblastic leukemia to acute monocytic leukemia at relapse.
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40.
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2010/01
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Tec protein tyrosine kinase inhibits CD25 expression in human T-lymphocyte.
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41.
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2009/12
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Gab1 transduces PI3K-mediated erythropoietin signals to the Erk pathway and regulates erythropoietin-dependent proliferation and survival of erythroid cells.
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42.
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2009/09
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Activated T-cell-mediated immunotherapy with a chimeric receptor against CD38 in B-cell non-Hodgkin lymphoma.
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43.
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2009/06
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Fludarabine and melphalan conditioning with tacrolimus as GVHD prophylaxis for allogeneic stem cell transplant recipients is an effective reduced-intensity combination regimen compared to the conventional regimen.
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44.
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2009/03
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Intravascular large B-cell lymphoma with FDG accumulation in the lung lacking CT/(67)gallium scintigraphy abnormality.
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45.
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2008/02
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Inhibition of Src reduces gemcitabine-induced cytotoxicity in human pancreatic cancer cell lines.
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46.
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2006/11
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Src transduces signaling via growth hormone (GH)-activated GH receptor (GHR) tyrosine-phosphorylating GHR and STAT5 in human leukemia cells.
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47.
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2005/04
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Cyclosporin A inhibits the early phase of NF-kappaB/RelA activation induced by CD28 costimulatory signaling to reduce the IL-2 expression in human peripheral T cells.
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48.
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2004/08
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Constitutive activation of PI3K is involved in the spontaneous proliferation of primary acute myeloid leukemia cells: direct evidence of PI3K activation.
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49.
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2004/06
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Constitutively activated phosphatidylinositol 3-kinase primes platelets from patients with chronic myelogenous leukemia for thrombopoietin-induced aggregation.
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50.
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2004/05
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Identification of p46 Shc expressed in the nuclei of hepatocytes with high proliferating activity: Study of regenerating rat liver.
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51.
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2004/03
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Analysis of the optimal blood sampling conditions for estimation of hematopoietic progenitor cell count by the SE-9000 automated hematolyzer.
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52.
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2001/10
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Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase.
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53.
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2001/10
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Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathway. Oncogene
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54.
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2001/09
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Growth hormone prevents Fas-induced apoptosis in lymphocytes through modulation of Bcl-2 and caspase-3.
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55.
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2000/08
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Mediation by the protein-tyrosine kinase Tec of signaling between the B cell antigen receptor and Dok-1.
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56.
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2000/02
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CD38 in hematopoiesis.
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57.
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2000/01
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CD38 ligation inhibits normal and leukemic myelopoiesis.
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58.
|
1999/10
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Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase.
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59.
|
1999/02
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CD38-mediated signaling events in murine pro-B cells expressing human CD38 with or without its cytoplasmic domain.
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60.
|
1998/02
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Expression and activation of the nonreceptor tyrosine kinase Tec in human B cells.
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61.
|
1997/07
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CD38 ligation in human B cell progenitors triggers tyrosine phosphorylation of CD19 and association of CD19 with lyn and phosphatidylinositol 3-kinase.
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62.
|
1997/04
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Antisense src expression inhibits tyrosine phosphorylation of Shc and its association with Grb2 and Sos which leads to MAP kinase activation in U937 human leukemia cells.
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63.
|
1996/12
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Human B-cell progenitors and bone marrow microenvironment.
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64.
|
1996/07
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CD38-mediated growth suppression of B-cell progenitors requires activation of phosphatidylinositol 3-kinase and involves its association with the protein product of the c-cbl proto-
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65.
|
1996/02
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Clinical relevance of BCL-2 overexpression in childhood acute lymphoblastic leukemia.
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66.
|
1996/01
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CD38 signal transduction in human B cell precursors. Rapid induction of tyrosine phosphorylation, activation of syk tyrosine kinase, and phosphorylation of phospholipase C-gamma and phosphatidylinositol 3-kinase.
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67.
|
1994/11
|
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Low-dose continuous subcutaneous infusion of granulocyte colony-stimulating factor for chemotherapy-induced neutropenia in acute myelogenous leukemia and its pharmacokinetics.
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68.
|
1994/06
|
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Antisense src expression inhibits U937 human leukemia cell proliferation in conjunction with reduction of c-myb expression.
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69.
|
1994/06
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Antisense src expression inhibits proliferation and erythropoietin-induced erythroid differentiation of K562 human leukemia cells.
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|
70.
|
2025/06
|
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Comparison of severe aplastic anaemia and lower risk hypoplastic myelodysplastic neoplasms: Critical role of megakaryocyte count in distinguishing aplastic anaemia from myelodysplastic neoplasms
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71.
|
2025/05/16
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|
Diphyllobothrium nihonkaiense detected in a mother and daughter
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72.
|
2025/03/25
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Response to Panic Values at Kawasaki Medical School Hospital
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73.
|
2025/03/22
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Pneumatic tube transport system carriers made from urethane contaminated with environmental pathogens
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74.
|
2024/05
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Clinical impact and characteristics of erythroid dysplasia in adult aplastic anaemia: Results from a multicentre registry
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75.
|
2024/01
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Real-world clinical characteristics of post-essential thrombocythemia and post-polycythemia vera myelofibrosis
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76.
|
2023/08/01
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Integrated genetic and clinical prognostic factors for aggressive adult T-cell leukemia/lymphoma
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77.
|
2023/07/01
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Nationwide prospective survey of secondary myelofibrosis in Japan: superiority of DIPSS-plus to MYSEC-PM as a survival risk model
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78.
|
2022/07
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Histone deacetylase inhibitor, panobinostat, exerts anti-proliferative effect with partial normalization from aberrant epigenetic states on granulosa cell tumor cell lines.
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79.
|
2022/02
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Immunohistopathological Analysis of Extramedullary Hematopoiesis and Angiogenesis of Spleen in a Case of Primary Myelofibrosis with Huge Splenomegaly
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80.
|
2021/10
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Whole-genome landscape of adult T-cell leukemia/lymphoma.
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81.
|
2021/09
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Single-Cell Analysis of the Multicellular Ecosystem in Viral Carcinogenesis by HTLV-1.
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82.
|
2021/05
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VLX1570 induces apoptosis through the generation of ROS and induction of ER stress on leukemia cell lines
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83.
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2021/03
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Association between microRNA-527 and glypican-3 in hepatocellular carcinoma
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84.
|
2020/12
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Higher average chemotherapy dose intensity improves prognosis in patients with aggressive adult T-cell leukemia/lymphoma
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|
85.
|
2020/02
|
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Clinical significance of soluble CADM1 as a novel marker for adult T-cell leukemia/lymphoma.
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86.
|
2018/06
|
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An MDS-derived cell line and a series of its sublines serve as an in vitro model for the leukemic evolution of MDS
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